CVCL_U112 - Rat Genome Database

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Cell Line : CVCL_U112 (NB4.437r) Homo sapiens

Symbol: CVCL_U112
Name: NB4.437r
RGD ID: 21146697
Cell Line Type: cancer cell line
Origin: Selected for resistance to: ChEBI; CHEBI:88334; AHPN (6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalenecarboxylic acid; Derived from sampling site: Bone marrow.
Gender: Female
Genomic Alteration: Sequence variation: Gene fusion; PML-RARA (from parent cell line); Sequence variation: Heterozygous for KRAS p.Ala18Asp (c.53C>A) (from parent cell line); Sequence variation: Homozygous for TP53 p.Arg248Gln (c.743G>A) (ClinVar=VCV000012356) (from parent cell line)
Derived From Cell Lines: CVCL_0005 (NB4)
Aliases: NB4-437r; NB4-G-437R
Disease(s): acute promyelocytic leukemia (DOID:0060318) [NCI:C3182,ORDO:520]

References
Additional References at PubMed
PMID:10753850   PMID:11704857  


Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_U112 CELLOSAURUS
NCIt C3182 CELLOSAURUS
Orphanet 520 CELLOSAURUS
Wikidata Q54907538 CELLOSAURUS