CVCL_KU45 - Rat Genome Database

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Cell Line : CVCL_KU45 (MCF7 Tet-On Advanced) Homo sapiens

Symbol: CVCL_KU45
Name: MCF7 Tet-On Advanced
RGD ID: 21146299
Cell Line Type: cancer cell line
Origin: Population: Caucasian; Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Gender: Female
Availability: Discontinued: Takara/Clontech; Catalog number 632108; Discontinued: Takara/Clontech; Catalog number 631153
Characteristics: Characteristics: Transfected with an advanced reverse tetracycline-controlled transactivator (rtTA2(S)-M2), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16
Genomic Alteration: Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line); Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line); Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR; Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del)
Derived From Cell Lines: CVCL_0031 (MCF-7)
Disease(s): invasive ductal carcinoma (DOID:3008) [NCI:C4194]

References

Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_KU45 CELLOSAURUS
Cellosaurus CVCL_KU45 CELLOSAURUS
NCIt C4194 CELLOSAURUS
Wikidata Q54904454 CELLOSAURUS