CVCL_2082 - Rat Genome Database

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Cell Line : CVCL_2082 (JOSK-I) Homo sapiens

Symbol: CVCL_2082
Name: JOSK-I
RGD ID: 21145368
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Pleural effusion.
Gender: Male
Phenotype: Doubling time: ~28-35 hours (DSMZ)
Genomic Alteration: Sequence variation: Gene fusion; PICALM-MLLT10 (CALM-AF10) (from parent cell line); Sequence variation: Hemizygous for PTEN p.Gly129fs*51 (c.387_388insCGCC) (from parent cell line); Sequence variation: Homozygous for TP53 c.559+1G>A (p.Val173Trpfs*59) (ClinVar=VCV000428908); Note=Splice donor mutation (from parent cell line)
Caution: Problematic cell line: Contaminated Shown to be a U-937 derivative (PubMed=10508494; PubMed=12592342; PubMed=20143388).
Groups: Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00135
Derived From Cell Lines: CVCL_0007 (U-937)
Aliases: JOSK-1
Disease(s): adult acute monocytic leukemia (DOID:0080149) [NCI:C8263]

References
Additional References at PubMed
PMID:3486043   PMID:9510473   PMID:10508494   PMID:12592342   PMID:20143388  


Additional Information

Database Acc Id Source(s)
BioSample SAMN03151980 CELLOSAURUS
Cell Line Ontology CLO_0007034 CELLOSAURUS
Cellosaurus CVCL_2082 CELLOSAURUS
COSMIC Samples 787438 CELLOSAURUS
  919120 CELLOSAURUS
  947371 CELLOSAURUS
DSMZ ACC-155 CELLOSAURUS
NCIt C8263 CELLOSAURUS
Orphanet 514 CELLOSAURUS
Wikidata Q54899045 CELLOSAURUS