Cell Line : CVCL_KZ32 (PathHunter HEK 293 ADRB2 Total GPCR Internalization) Homo sapiens
Symbol:
CVCL_KZ32
Name:
PathHunter HEK 293 ADRB2 Total GPCR Internalization
RGD ID:
21144812
Cell Line Type:
transformed cell line
Origin:
Transformant: Adenovirus 5(NCBI-Taxonomy; 28285); Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Gender:
Female
Characteristics:
Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.