CVCL_KZ32 - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Cell Line : CVCL_KZ32 (PathHunter HEK 293 ADRB2 Total GPCR Internalization) Homo sapiens

Symbol: CVCL_KZ32
Name: PathHunter HEK 293 ADRB2 Total GPCR Internalization
RGD ID: 21144812
Cell Line Type: transformed cell line
Origin: Transformant: Adenovirus 5(NCBI-Taxonomy; 28285); Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Gender: Female
Characteristics: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Genomic Alteration: Transfected with: HGNC; 286; ADRB2
Related Genes: ADRB2  
Derived From Cell Lines: CVCL_0045 (HEK293)
Aliases: PathHunter ADRB2 Total GPCR Internalization HEK 293

References

Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_KZ32 CELLOSAURUS
DiscoverX 93-0800C1 CELLOSAURUS
Wikidata Q54938010 CELLOSAURUS