CVCL_KZ53 - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Cell Line : CVCL_KZ53 (PathHunter HEK 293 GPR152 beta-arrestin) Homo sapiens

Symbol: CVCL_KZ53
Name: PathHunter HEK 293 GPR152 beta-arrestin
RGD ID: 21144789
Cell Line Type: transformed cell line
Origin: Transformant: Adenovirus 5(NCBI-Taxonomy; 28285); Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Gender: Female
Characteristics: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA) Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Genomic Alteration: Transfected with: HGNC; 23622; GPR152; Transfected with: HGNC; 712; ARRB2
Related Genes: ARRB2   GPR152  
Derived From Cell Lines: CVCL_0045 (HEK293)

References

Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_KZ53 CELLOSAURUS
DiscoverX 93-0384C1A CELLOSAURUS
Wikidata Q54938034 CELLOSAURUS