CVCL_TH52 - Rat Genome Database

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Cell Line : CVCL_TH52 (HAP1 PTH1R (-)) Homo sapiens

Symbol: CVCL_TH52
Name: HAP1 PTH1R (-)
RGD ID: 21143227
Cell Line Type: cancer cell line
Origin: Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Gender: Male
Genomic Alteration: Knockout cell: Method=CRISPR/Cas9; HGNC; 9608; PTH1R; Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line)
Groups: Group: Haploid karyotype cell line
Related Genes: PTH1R  
Derived From Cell Lines: CVCL_Y019 (HAP1)
Aliases: HZGHC006073c010; PTH1R knockout cell line 119bp deletion
Disease(s): chronic myeloid leukemia (DOID:8552) [NCI:C3174,ORDO:521]

References

Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_TH52 CELLOSAURUS
Cellosaurus CVCL_TH52 CELLOSAURUS
Horizon_Discovery HZGHC006073c010 CELLOSAURUS
NCIt C3174 CELLOSAURUS
Orphanet 521 CELLOSAURUS
Wikidata Q54879378 CELLOSAURUS