CVCL_TF39 - Rat Genome Database

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Cell Line : CVCL_TF39 (HAP1 PPM1E (-) 3) Homo sapiens

Symbol: CVCL_TF39
Name: HAP1 PPM1E (-) 3
RGD ID: 21142026
Cell Line Type: cancer cell line
Origin: Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Gender: Male
Genomic Alteration: Knockout cell: Method=CRISPR/Cas9; HGNC; 19322; PPM1E; Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line)
Groups: Group: Haploid karyotype cell line
Related Genes: PPM1E  
Derived From Cell Lines: CVCL_Y019 (HAP1)
Aliases: HZGHC003115c001; PPM1E knockout cell line 1bp insertion
Disease(s): chronic myeloid leukemia (DOID:8552) [NCI:C3174,ORDO:521]

References

Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_TF39 CELLOSAURUS
Cellosaurus CVCL_TF39 CELLOSAURUS
Horizon_Discovery HZGHC003115c001 CELLOSAURUS
NCIt C3174 CELLOSAURUS
Orphanet 521 CELLOSAURUS
Wikidata Q54877118 CELLOSAURUS