CVCL_1096 - Rat Genome Database

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Cell Line : CVCL_1096 (C2BBe1) Homo sapiens

Symbol: CVCL_1096
Name: C2BBe1
RGD ID: 21134243
Cell Line Type: cancer cell line
Origin: Population: Caucasian; Derived from sampling site: Colon.
Gender: Male
Research Use: Omics: Deep exome analysis; Omics: Deep quantitative phosphoproteome analysis; Omics: Deep quantitative proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: Protein expression by reverse-phase protein arrays; Omics: shRNA library screening; Omics: SNP array analysis; Omics: Transcriptome analysis
Phenotype: Doubling time: 44 hours (PubMed=25984343); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Homozygous for APC p.Gln1367Ter (c.4099C>T) (ClinVar=VCV000376060) (ATCC; CCLE; Cosmic-CLP); Sequence variation: Heterozygous for CTNNB1 p.Gly245Ala (c.734G>C) (CCLE; Cosmic-CLP); Sequence variation: Homozygous for SMAD4 p.Asp351His (c.1051G>C) (ClinVar=VCV000375998) (CCLE; Cosmic-CLP); Sequence variation: Homozygous for TP53 p.Glu204Ter (c.610G>T) (ClinVar=VCV000977783) (CCLE; Cosmic-CLP)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: MD Anderson Cell Lines Project
Description: Genome ancestry: African=0%; Native American=0%; East Asian, North=1.84%; East Asian, South=0.11%; South Asian=0%; European, North=57.43%; European, South=40.62% (PubMed=30894373)
Derived From Cell Lines: CVCL_0025 (Caco-2)
Aliases: BBE; C2BBe 1; C2BBE1; Caco-2 BBe; Caco-2/BBe; Caco-2/BBe 1; Caco-2BBe; Caco2-BBE; Caco2BBe
Disease(s): colon adenocarcinoma (DOID:234) [NCI:C4349]

References
Additional References at PubMed
PMID:1506435   PMID:15868485   PMID:20164919   PMID:20570890   PMID:20606684   PMID:22460905   PMID:25485619   PMID:25984343   PMID:27397505   PMID:28196595   PMID:28854368   PMID:29444439  
PMID:30894373   PMID:31068700  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
ATCC CRL-2102 CELLOSAURUS
BCRC 60182 CELLOSAURUS
BCRJ 0270 CELLOSAURUS
BioSample SAMN03472296 CELLOSAURUS
  SAMN10987952 CELLOSAURUS
BTO BTO_0005156 CELLOSAURUS
Cell Line Ontology CLO_0002108 CELLOSAURUS
Cell Model Passports SIDM01233 CELLOSAURUS
Cellosaurus CVCL_1096 CELLOSAURUS
ChEMBL-Cells CHEMBL3308231 CELLOSAURUS
ChEMBL-Targets CHEMBL2366283 CELLOSAURUS
COSMIC Samples 1479619 CELLOSAURUS
  687516 CELLOSAURUS
  910700 CELLOSAURUS
Cosmic-CLP 910700 CELLOSAURUS
DepMap ACH-000009 CELLOSAURUS
EFO EFO_0006546 CELLOSAURUS
GDSC 910700 CELLOSAURUS
GEO GSM1669635 CELLOSAURUS
  GSM886897 CELLOSAURUS
  GSM887962 CELLOSAURUS
LiGeA CCLE_083 CELLOSAURUS
LINCS_LDP LCL-1296 CELLOSAURUS
NCIt C4349 CELLOSAURUS
PharmacoDB C2BBe1_153_2019 CELLOSAURUS
PRIDE PXD005235 CELLOSAURUS
Progenetix CVCL_1096 CELLOSAURUS
Wikidata Q54808117 CELLOSAURUS