CVCL_SF57 - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Cell Line : CVCL_SF57 (HAP1 BRD3 (-) 2) Homo sapiens

Symbol: CVCL_SF57
Name: HAP1 BRD3 (-) 2
RGD ID: 21120811
Cell Line Type: cancer cell line
Origin: Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Gender: Male
Genomic Alteration: Knockout cell: Method=CRISPR/Cas9; HGNC; 1104; BRD3; Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line)
Groups: Group: Haploid karyotype cell line
Related Genes: BRD3  
Derived From Cell Lines: CVCL_Y019 (HAP1)
Aliases: BRD3 knockout cell line 8bp deletion; HZGHC005081c002
Disease(s): chronic myeloid leukemia (DOID:8552) [NCI:C3174,ORDO:521]

References
Additional References at PubMed
PMID:31659326  


Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_SF57 CELLOSAURUS
Cellosaurus CVCL_SF57 CELLOSAURUS
Horizon_Discovery HZGHC005081c002 CELLOSAURUS
NCIt C3174 CELLOSAURUS
Orphanet 521 CELLOSAURUS
Wikidata Q54873004 CELLOSAURUS