CVCL_0633 - Rat Genome Database

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Cell Line : CVCL_0633 (U-118MG) Homo sapiens

Symbol: CVCL_0633
Name: U-118MG
RGD ID: 21120756
Cell Line Type: cancer cell line
Gender: Male
Research Use: Omics: CNV analysis; Omics: Deep exome analysis; Omics: Deep quantitative proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: SNP array analysis; Omics: Transcriptome analysis
Availability: Discontinued: ATCC; CRL-7712; true.
Phenotype: Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Mutation; IDH1; none detected (PubMed=19435942); Sequence variation: Homozygous for PTEN c.1026+1G>T (IVS8+1G>T) (ClinVar=VCV000635377); Note=Splice donor mutation (PubMed=10560660; Cosmic-CLP); Sequence variation: Homozygous for TP53 p.Arg213Gln (c.638G>A) (ClinVar=VCV000135359) (PubMed=10416987; Cosmic-CLP)
Caution: Problematic cell line: Contaminated Shown to be a U-138MG derivative (PubMed=20143388).
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982); Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00350
Description: Genome ancestry: African=1.71%; Native American=0%; East Asian, North=1.75%; East Asian, South=0%; South Asian=0%; European, North=96.54%; European, South=0% (PubMed=30894373)
Derived From Cell Lines: CVCL_0020 (U-138MG)
Child Cell Lines: CVCL_D317 (1181N1)
CVCL_S097 (KC)
CVCL_T447 (EH-118MG)
Aliases: 118 MG; 118MG; U-118 MG; U-118-MG; U118; U118-MG; U118MG
Disease(s): autosomal dominant cerebellar ataxia (DOID:1441) [ORDO:94]
malignant astrocytoma (DOID:3069) [NCI:C60781]

References
Additional References at PubMed
PMID:327080   PMID:450131   PMID:833871   PMID:2253244   PMID:2454731   PMID:3518877   PMID:3675803   PMID:4134536   PMID:4312117   PMID:4313504   PMID:4337530   PMID:4369403  
PMID:6220172   PMID:6260907   PMID:7017212   PMID:7459858   PMID:9220028   PMID:10416987   PMID:10560660   PMID:11414198   PMID:16697959   PMID:19365568   PMID:19435942   PMID:20143388  
PMID:20164919   PMID:22460905   PMID:22570425   PMID:27397505   PMID:27582061   PMID:30894373   PMID:31068700   PMID:31978347  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
ATCC CRL-7712 CELLOSAURUS
  HTB-15 CELLOSAURUS
BioSample SAMN03151974 CELLOSAURUS
  SAMN03472723 CELLOSAURUS
  SAMN10988042 CELLOSAURUS
BTO BTO_0004605 CELLOSAURUS
CCRID 3131C0001001200022 CELLOSAURUS
Cell Line Ontology CLO_0009451 CELLOSAURUS
Cell Model Passports SIDM01193 CELLOSAURUS
Cellosaurus CVCL_0633 CELLOSAURUS
ChEMBL-Cells CHEMBL3308793 CELLOSAURUS
ChEMBL-Targets CHEMBL1075602 CELLOSAURUS
COSMIC Samples 1175822 CELLOSAURUS
  1217672 CELLOSAURUS
  1571919 CELLOSAURUS
  1610738 CELLOSAURUS
  2301554 CELLOSAURUS
  2367553 CELLOSAURUS
  2550362 CELLOSAURUS
  2668299 CELLOSAURUS
  2701084 CELLOSAURUS
  687588 CELLOSAURUS
  849852 CELLOSAURUS
  849878 CELLOSAURUS
  920817 CELLOSAURUS
Cosmic-CLP 687588 CELLOSAURUS
DepMap ACH-000040 CELLOSAURUS
DOI 10.1007/0-306-46861-1_11 CELLOSAURUS
  10.1007/978-1-4757-1647-4_7 CELLOSAURUS
  10.1016/B978-0-12-333530-2.50005-8 CELLOSAURUS
GDSC 687588 CELLOSAURUS
GEO GSM101671 CELLOSAURUS
  GSM101672 CELLOSAURUS
  GSM1374968 CELLOSAURUS
  GSM1374969 CELLOSAURUS
  GSM1670554 CELLOSAURUS
  GSM888812 CELLOSAURUS
LiGeA CCLE_075 CELLOSAURUS
LINCS_LDP LCL-1358 CELLOSAURUS
NCIt C60781 CELLOSAURUS
Orphanet 94 CELLOSAURUS
PharmacoDB U118MG_1616_2019 CELLOSAURUS
Progenetix CVCL_0633 CELLOSAURUS
Wikidata Q54973503 CELLOSAURUS