CVCL_0624 - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Cell Line : CVCL_0624 (MOLT-3) Homo sapiens

Symbol: CVCL_0624
Name: MOLT-3
RGD ID: 21120748
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Peripheral blood.
Gender: Male
Research Use: Omics: Deep exome analysis; Omics: Deep RNAseq analysis; Omics: SNP array analysis
Phenotype: Doubling time: 24-48 hours (CLS); ~40 hours (DSMZ); Microsatellite instability: Instable (MSI) (PubMed=31068700)
Genomic Alteration: Sequence variation: Heterozygous for NOTCH1 p.Leu1600Pro (c.4799T>C) (PubMed=15472075; CCLE); Sequence variation: Heterozygous for NOTCH1 p.Pro2514Argfs*4 (c.7541_7542delCT) (ClinVar=VCV000581973) (PubMed=15472075; CCLE); Sequence variation: Heterozygous for NRAS p.Gln61Lys (c.181C>A) (ClinVar=VCV000073058) (CCLE); Sequence variation: Homozygous for PTEN p.Lys267Argfs*9 (c.800delA) (p.Leu265fs; c.795delA) (ClinVar=VCV000092828) (CCLE)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project
Description: Genome ancestry: African=0.91%; Native American=0%; East Asian, North=2.31%; East Asian, South=0%; South Asian=0.44%; European, North=66.02%; European, South=30.32% (PubMed=30894373)
Child Cell Lines: CVCL_M774 (MOLT-3/Z29)
CVCL_N031 (MOVP-3)
CVCL_S652 (MOLT-3/MTXt)
CVCL_S653 (MOLT-3/TMQ200)
CVCL_S655 (MOLT-3/TMQ2500)
CVCL_S656 (MOLT-3/TMQ800)
CVCL_S658 (MOLT-3/MTX10000)
CVCL_S659 (MOLT-3/MTX200)
CVCL_S660 (MOLT-3/MTX.P-9)
CVCL_S661 (MOLT-3/ZD1694.C)
CVCL_S662 (MOLT-3/ZD1694.P9)
Originate from same individual as: CVCL_0013 (MOLT-4)
Aliases: MOLT 3; Molt-3; MOLT3
Disease(s): T-cell adult acute lymphocytic leukemia (DOID:5602) [NCI:C9142]

References
Additional References at PubMed
PMID:327080   PMID:2846092   PMID:3518877   PMID:3856477   PMID:4547172   PMID:4567231   PMID:6220172   PMID:6600440   PMID:7630190   PMID:8547074   PMID:8608962   PMID:9738977  
PMID:9787181   PMID:9933131   PMID:11986953   PMID:12623853   PMID:15472075   PMID:17170727   PMID:20215515   PMID:30285677   PMID:30894373   PMID:31068700  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2770 CELLOSAURUS
  E-MTAB-38 CELLOSAURUS
ATCC CRL-1552 CELLOSAURUS
BCRC 60106 CELLOSAURUS
BioSample SAMN03470846 CELLOSAURUS
  SAMN03471394 CELLOSAURUS
  SAMN03472164 CELLOSAURUS
  SAMN03473404 CELLOSAURUS
  SAMN10989586 CELLOSAURUS
BTO BTO_0001081 CELLOSAURUS
Cell Line Ontology CLO_0007824 CELLOSAURUS
  CLO_0051008 CELLOSAURUS
Cell Model Passports SIDM00153 CELLOSAURUS
Cellosaurus CVCL_0624 CELLOSAURUS
ChEMBL-Cells CHEMBL3307556 CELLOSAURUS
ChEMBL-Targets CHEMBL614176 CELLOSAURUS
COSMIC Samples 1191701 CELLOSAURUS
  1281377 CELLOSAURUS
  1524845 CELLOSAURUS
  2301561 CELLOSAURUS
  2361367 CELLOSAURUS
  2602923 CELLOSAURUS
  724815 CELLOSAURUS
  850193 CELLOSAURUS
  913410 CELLOSAURUS
  999756 CELLOSAURUS
DepMap ACH-000964 CELLOSAURUS
DOI 10.1016/B978-0-12-221970-2.50457-5 CELLOSAURUS
DSMZ ACC-84 CELLOSAURUS
ECACC 90021901 CELLOSAURUS
EFO EFO_0005265 CELLOSAURUS
GEO GSM236793 CELLOSAURUS
  GSM236829 CELLOSAURUS
IGRhCellID MOLT3 CELLOSAURUS
JCRB JCRB9048 CELLOSAURUS
LiGeA CCLE_717 CELLOSAURUS
NCIt C9142 CELLOSAURUS
Orphanet 99861 CELLOSAURUS
PharmacoDB MOLT3_957_2019 CELLOSAURUS
Progenetix CVCL_0624 CELLOSAURUS
RCB RCB1164 CELLOSAURUS
Wikidata Q54906351 CELLOSAURUS