CVCL_0566 - Rat Genome Database

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Cell Line : CVCL_0566 (U266B1) Homo sapiens

Symbol: CVCL_0566
Name: U266B1
RGD ID: 21120201
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Peripheral blood.
Gender: Male
Research Use: Omics: Array-based CGH; Omics: Deep exome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: Protein expression by reverse-phase protein arrays; Omics: SNP array analysis; Omics: Transcriptome analysis
Availability: Discontinued: BCRJ; 0240; probable
Characteristics: Characteristics: Produces IgE lambda
Phenotype: Doubling time: 108-144 hours (PubMed=4104421); ~55 hours (DSMZ); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Heterozygous for BRAF p.Lys601Asn (c.1803A>T) (ClinVar=VCV000376285) (CCLE; Cosmic-CLP); Sequence variation: Heterozygous for MSH6 p.Gly141Asp (c.422G>A) (CCLE; Cosmic-CLP); Sequence variation: Homozygous for TP53 p.Ala161Thr (c.481G>A) (ClinVar=VCV000161518) (PubMed=21173094; CCLE; Cosmic-CLP); Sequence variation: Homozygous for TRAF3 p.Lys550Leufs*3 (c.1648_1649insT) (PubMed=17692805)
Groups: Group: Hybridoma fusion partner cell line; Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: LL-100 blood cancer cell line panel; Part of: MD Anderson Cell Lines Project; Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981)
Description: HLA typing: A*02:01,03; B*07,40; C*03:04,07 (Direct_author_submission); Genome ancestry: African=0%; Native American=0%; East Asian, North=2.78%; East Asian, South=0.29%; South Asian=0.45%; European, North=80.76%; European, South=15.72% (PubMed=30894373)
Notes: Miscellaneous: HLA typing from personal communication of Pellat-Deceunynck C
Child Cell Lines: CVCL_0015 (U-266/70)
CVCL_0016 (U-266/84)
CVCL_4974 (SKO-007)
CVCL_C828 (U266R)
CVCL_C833 (AF10)
CVCL_GZ72 (U266/ADM)
CVCL_J235 (FU-266)
CVCL_T031 (U266/velR)
CVCL_VJ36 (U266/BR)
Originate from same individual as: CVCL_JA36 (U255)
CVCL_W412 (U268)
Aliases: 266 Bl; U 266; U-266; U266; U266 B1; U266 Bl; U266-B1; U266BL; U266S
Disease(s): multiple myeloma (DOID:9538) [NCI:C3242,ORDO:29073]

References
Additional References at PubMed
PMID:1643757   PMID:1720489   PMID:2140233   PMID:2537114   PMID:4097745   PMID:4104421   PMID:8943038   PMID:9685479   PMID:10087940   PMID:10557056   PMID:10583232   PMID:10936422  
PMID:11154231   PMID:11157491   PMID:11429052   PMID:14555701   PMID:15215163   PMID:16956823   PMID:17171682   PMID:17229644   PMID:17692805   PMID:18647998   PMID:20164919   PMID:20215515  
PMID:21173094   PMID:22460905   PMID:22806891   PMID:23074853   PMID:23992230   PMID:25485619   PMID:25688540   PMID:27397505   PMID:28196595   PMID:30285677   PMID:30545397   PMID:30894373  
PMID:31068700   PMID:31160637  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-38 CELLOSAURUS
  E-MTAB-7721 CELLOSAURUS
  E-MTAB-7722 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
  E-TABM-937 CELLOSAURUS
ATCC TIB-196 CELLOSAURUS
BCRC 60437 CELLOSAURUS
BCRJ 0240 CELLOSAURUS
BioSample SAMN01821605 CELLOSAURUS
  SAMN01821669 CELLOSAURUS
  SAMN03472935 CELLOSAURUS
  SAMN10987866 CELLOSAURUS
BTO BTO_0001594 CELLOSAURUS
CCRID 3111C0001CCC000684 CELLOSAURUS
  3142C0001000000327 CELLOSAURUS
  3142C0001000000351 CELLOSAURUS
Cell Line Ontology CLO_0009457 CELLOSAURUS
  CLO_0009458 CELLOSAURUS
Cell Model Passports SIDM00417 CELLOSAURUS
Cellosaurus CVCL_0566 CELLOSAURUS
ChEMBL-Cells CHEMBL3308535 CELLOSAURUS
ChEMBL-Targets CHEMBL2366315 CELLOSAURUS
COSMIC Samples 1424220 CELLOSAURUS
  1483078 CELLOSAURUS
  1762463 CELLOSAURUS
  1889513 CELLOSAURUS
  2081409 CELLOSAURUS
  2159571 CELLOSAURUS
  2367281 CELLOSAURUS
  2391806 CELLOSAURUS
  2809754 CELLOSAURUS
  720795 CELLOSAURUS
  742953 CELLOSAURUS
  753615 CELLOSAURUS
  759903 CELLOSAURUS
  759912 CELLOSAURUS
  760401 CELLOSAURUS
  760647 CELLOSAURUS
  886087 CELLOSAURUS
  888019 CELLOSAURUS
  991555 CELLOSAURUS
Cosmic-CLP 753615 CELLOSAURUS
DepMap ACH-000626 CELLOSAURUS
DOI 10.1016/B978-0-12-221970-2.50457-5 CELLOSAURUS
DSMZ ACC-9 CELLOSAURUS
ECACC 85051003 CELLOSAURUS
EFO EFO_0001254 CELLOSAURUS
GDSC 753615 CELLOSAURUS
GEO GSM1374970 CELLOSAURUS
  GSM143345 CELLOSAURUS
  GSM1670556 CELLOSAURUS
  GSM545498 CELLOSAURUS
  GSM545499 CELLOSAURUS
  GSM562821 CELLOSAURUS
  GSM827442 CELLOSAURUS
  GSM887721 CELLOSAURUS
  GSM888815 CELLOSAURUS
IGRhCellID U266B1 CELLOSAURUS
LiGeA CCLE_465 CELLOSAURUS
LINCS_LDP LCL-2050 CELLOSAURUS
Lonza 106 CELLOSAURUS
  807 CELLOSAURUS
NCIt C3242 CELLOSAURUS
Orphanet 29073 CELLOSAURUS
PharmacoDB U266B1_1630_2019 CELLOSAURUS
Progenetix CVCL_0566 CELLOSAURUS
Wikidata Q54973634 CELLOSAURUS