CVCL_IY15 - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Cell Line : CVCL_IY15 (NB4R) Homo sapiens

Symbol: CVCL_IY15
Name: NB4R
RGD ID: 21116824
Cell Line Type: cancer cell line
Origin: Selected for resistance to: ChEBI; CHEBI:15367; All-trans-retinoic acid (ATRA; Derived from sampling site: Bone marrow.
Gender: Female
Genomic Alteration: Sequence variation: Gene fusion; PML-RARA (from parent cell line); Sequence variation: Heterozygous for KRAS p.Ala18Asp (c.53C>A) (from parent cell line); Sequence variation: Homozygous for TP53 p.Arg248Gln (c.743G>A) (ClinVar=VCV000012356) (from parent cell line)
Derived From Cell Lines: CVCL_0005 (NB4)
Disease(s): acute promyelocytic leukemia (DOID:0060318) [NCI:C3182,ORDO:520]

References

Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_IY15 CELLOSAURUS
NCIt C3182 CELLOSAURUS
Orphanet 520 CELLOSAURUS
Wikidata Q54907540 CELLOSAURUS