CVCL_0012 - Rat Genome Database

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Cell Line : CVCL_0012 (LP-1) Homo sapiens

Symbol: CVCL_0012
Name: LP-1
RGD ID: 21113476
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Peripheral blood.
Gender: Female
Research Use: Omics: Array-based CGH; Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: Protein expression by reverse-phase protein arrays; Omics: SNP array analysis; Omics: Transcriptome analysis
Characteristics: Characteristics: Produces IgG lambda
Phenotype: Doubling time: 50 hours (PubMed=2784066); 48 hours (PubMed=25984343); 35-80 hours, depending on cell density (DSMZ); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Gene fusion; IGH-WHSC1 (PubMed=31160637); Sequence variation: FGFR3 p.Phe384Leu (c.1150T>C) (F386L) (ClinVar=VCV000134404) (PubMed=11157491); Sequence variation: Homozygous for TRAF3 p.Lys286Ilefs*7 (c.857_870delAGAGCATACAAAGT) (PubMed=17692805); Sequence variation: Homozygous for TP53 p.Glu286Lys (c.856G>A) (ClinVar=VCV000183752) (PubMed=21173094; Cosmic-CLP)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: LL-100 blood cancer cell line panel; Part of: MD Anderson Cell Lines Project
Description: HLA typing: A*03,24; B*07,18; C*07 (PubMed=25688540); Genome ancestry: African=0.21%; Native American=0%; East Asian, North=3.2%; East Asian, South=0%; South Asian=2.32%; European, North=42.82%; European, South=51.44% (PubMed=30894373)
Aliases: LP1
Disease(s): multiple myeloma (DOID:9538) [NCI:C3242,ORDO:29073]

References
Additional References at PubMed
PMID:2784066   PMID:10583232   PMID:10936422   PMID:11157491   PMID:16956823   PMID:17171682   PMID:17692805   PMID:18647998   PMID:18700954   PMID:20164919   PMID:21173094   PMID:22460905  
PMID:25485619   PMID:25688540   PMID:25984343   PMID:27397505   PMID:28196595   PMID:30285677   PMID:30545397   PMID:30894373   PMID:31068700   PMID:31160637  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-7721 CELLOSAURUS
  E-MTAB-7722 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
  E-TABM-937 CELLOSAURUS
BioSample SAMN03472929 CELLOSAURUS
  SAMN10988493 CELLOSAURUS
BTO BTO_0005912 CELLOSAURUS
Cell Line Ontology CLO_0007379 CELLOSAURUS
Cell Model Passports SIDM00340 CELLOSAURUS
Cellosaurus CVCL_0012 CELLOSAURUS
ChEMBL-Cells CHEMBL3308171 CELLOSAURUS
ChEMBL-Targets CHEMBL2366066 CELLOSAURUS
COSMIC Samples 2081397 CELLOSAURUS
  2367290 CELLOSAURUS
  2391810 CELLOSAURUS
  2809761 CELLOSAURUS
  720763 CELLOSAURUS
  759910 CELLOSAURUS
  907791 CELLOSAURUS
Cosmic-CLP 907791 CELLOSAURUS
DepMap ACH-000204 CELLOSAURUS
DOI 10.1016/B978-0-12-221970-2.50457-5 CELLOSAURUS
DSMZ ACC-41 CELLOSAURUS
EFO EFO_0003055 CELLOSAURUS
GDSC 907791 CELLOSAURUS
GEO GSM1374631 CELLOSAURUS
  GSM143335 CELLOSAURUS
  GSM1670057 CELLOSAURUS
  GSM290302 CELLOSAURUS
  GSM562813 CELLOSAURUS
  GSM887276 CELLOSAURUS
  GSM888351 CELLOSAURUS
LiGeA CCLE_549 CELLOSAURUS
LINCS_LDP LCL-2046 CELLOSAURUS
Lonza 129 CELLOSAURUS
NCIt C3242 CELLOSAURUS
Orphanet 29073 CELLOSAURUS
PharmacoDB LP1_858_2019 CELLOSAURUS
Progenetix CVCL_0012 CELLOSAURUS
Wikidata Q54902910 CELLOSAURUS