CVCL_0011 - Rat Genome Database

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Cell Line : CVCL_0011 (KM-3) Homo sapiens

Symbol: CVCL_0011
Name: KM-3
RGD ID: 21113473
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Peripheral blood.
Gender: Female
Genomic Alteration: Sequence variation: Gene fusion; ETV6-RUNX1 (TEL-AML1) (from parent cell line); Sequence variation: Homozygous for PTEN p.Arg173Cys (c.517C>T) (ClinVar=VCV000189500) (from parent cell line); Sequence variation: Heterozygous for TP53 p.Arg181Cys (c.541C>T) (ClinVar=VCV000142624) (from parent cell line)
Caution: Problematic cell line: Contaminated Shown to be a Reh derivative (PubMed=12592342; PubMed=20143388).
Groups: Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00226
Derived From Cell Lines: CVCL_1650 (Reh)
Aliases: KM3
Disease(s): childhood B-cell acute lymphoblastic leukemia (DOID:0080146) [NCI:C9140]

Additional References at PubMed
PMID:68013   PMID:6954533   PMID:12592342   PMID:20143388  

Additional Information

Database Acc Id Source(s)
BioSample SAMN03151905 CELLOSAURUS
Cellosaurus CVCL_0011 CELLOSAURUS
Orphanet 99860 CELLOSAURUS
Wikidata Q54900042 CELLOSAURUS