CVCL_0001 - Rat Genome Database

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Cell Line : CVCL_0001 (HEL) Homo sapiens

Symbol: CVCL_0001
Name: HEL
RGD ID: 21113445
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Peripheral blood.
Gender: Male
Research Use: Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep quantitative proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: SNP array analysis; Omics: Transcriptome analysis
Phenotype: Doubling time: ~24 hours (PubMed=6177045); ~36 hours (DSMZ); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Homozygous for JAK2 p.Val617Phe (c.1849G>T) (ClinVar=VCV000014662) (PubMed=16408098); Sequence variation: Homozygous for TP53 p.Met133Lys (c.398T>A) (CCLE; Cosmic-CLP)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: LL-100 blood cancer cell line panel
Description: Genome ancestry: African=2.4%; Native American=1.79%; East Asian, North=3.9%; East Asian, South=0%; South Asian=5.12%; European, North=13.33%; European, South=73.45% (PubMed=30894373)
Notes: Miscellaneous: Originally the patient was suffering from Hodgkin lymphoma
Child Cell Lines: CVCL_2481 (HEL 92.1.7)
CVCL_4360 (Dami)
CVCL_KS72 (CellSensor irf1-bla HEL)
CVCL_RS48 (HELrARA-C2mug/ML)
Aliases: GM06141; GM06141B; Hel; Human ErythroLeukemia
Disease(s): Acute Erythroblastic Leukemia (DOID:9002149) [NCI:C7152]

References
Additional References at PubMed
PMID:6177045   PMID:8558913   PMID:9290701   PMID:9510473   PMID:9738977   PMID:11021758   PMID:14504097   PMID:16408098   PMID:20164919   PMID:22460905   PMID:23955599   PMID:25485619  
PMID:27277069   PMID:27397505   PMID:29533902   PMID:30285677   PMID:30894373   PMID:31068700   PMID:31160637   PMID:31978347  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-7721 CELLOSAURUS
  E-MTAB-7722 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
BioSample SAMN03471056 CELLOSAURUS
  SAMN03472269 CELLOSAURUS
  SAMN10987697 CELLOSAURUS
BTO BTO_0000565 CELLOSAURUS
CCRID 3131C0001000700071 CELLOSAURUS
  3142C0001000000070 CELLOSAURUS
Cell Line Ontology CLO_0003679 CELLOSAURUS
  CLO_0023565 CELLOSAURUS
Cell Model Passports SIDM00594 CELLOSAURUS
CelloPub CLPUB00447 CELLOSAURUS
Cellosaurus CVCL_0001 CELLOSAURUS
ChEMBL-Cells CHEMBL3308090 CELLOSAURUS
ChEMBL-Targets CHEMBL613888 CELLOSAURUS
Coriell GM06141 CELLOSAURUS
COSMIC Samples 1012051 CELLOSAURUS
  1013868 CELLOSAURUS
  1037665 CELLOSAURUS
  1070698 CELLOSAURUS
  1078733 CELLOSAURUS
  1122162 CELLOSAURUS
  1127268 CELLOSAURUS
  1139508 CELLOSAURUS
  1139638 CELLOSAURUS
  1140092 CELLOSAURUS
  1151879 CELLOSAURUS
  1168467 CELLOSAURUS
  1170892 CELLOSAURUS
  1171333 CELLOSAURUS
  1176583 CELLOSAURUS
  1191710 CELLOSAURUS
  1192825 CELLOSAURUS
  1601067 CELLOSAURUS
  1604866 CELLOSAURUS
  1633512 CELLOSAURUS
  1943609 CELLOSAURUS
  2089667 CELLOSAURUS
  2131538 CELLOSAURUS
  2306207 CELLOSAURUS
  2649243 CELLOSAURUS
  787432 CELLOSAURUS
  798663 CELLOSAURUS
  850392 CELLOSAURUS
  907053 CELLOSAURUS
  919128 CELLOSAURUS
  924040 CELLOSAURUS
  947363 CELLOSAURUS
  975251 CELLOSAURUS
  976722 CELLOSAURUS
  994176 CELLOSAURUS
  996314 CELLOSAURUS
Cosmic-CLP 907053 CELLOSAURUS
DepMap ACH-000004 CELLOSAURUS
DOI 10.1007/978-1-4757-1647-4_13 CELLOSAURUS
DSMZ ACC-11 CELLOSAURUS
EFO EFO_0006579 CELLOSAURUS
GDSC 907053 CELLOSAURUS
GEO GSM1028243 CELLOSAURUS
  GSM1446763 CELLOSAURUS
  GSM1669874 CELLOSAURUS
  GSM482506 CELLOSAURUS
  GSM743410 CELLOSAURUS
  GSM887077 CELLOSAURUS
  GSM888147 CELLOSAURUS
JCRB JCRB0062 CELLOSAURUS
LiGeA CCLE_453 CELLOSAURUS
LINCS_LDP LCL-1053 CELLOSAURUS
NCIt C7152 CELLOSAURUS
Orphanet 318 CELLOSAURUS
PharmacoDB HEL_534_2019 CELLOSAURUS
Progenetix CVCL_0001 CELLOSAURUS
Wikidata Q54882501 CELLOSAURUS