CVCL_0002 - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Cell Line : CVCL_0002 (HL-60) Homo sapiens

Symbol: CVCL_0002
Name: HL-60
RGD ID: 21113444
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Peripheral blood.
Gender: Female
Research Use: Biotechnology: Used a source of mitochondrial DNA for USA forensic testing; Omics: Array-based CGH; Omics: Cell surface proteome; Omics: CNV analysis; Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: H3K4me3 ChIP-seq epigenome analysis; Omics: Mitochondrial genome sequenced; Omics: N-glycan profiling; Omics: Protein expression by reverse-phase protein arrays; Omics: shRNA library screening; Omics: SNP array analysis; Omics: Transcriptome analysis
Availability: Discontinued: JCRB; NIHS0086; true
Phenotype: Doubling time: 16 hours (PubMed=8343448); 28 hours (PubMed=25984343); ~40 hours (DSMZ); Microsatellite instability: Stable (MSS) (PubMed=12661003; Sanger)
Genomic Alteration: Sequence variation: Homozygous for CDKN2A p.Arg80Ter (c.238C>T) (p.Pro94Leu; c.281C>T) (ClinVar=VCV000009409) (PubMed=17088437; CCLE; Cosmic-CLP); Sequence variation: Heterozygous for NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (PubMed=12068308; PubMed=17088437; CCLE; Cosmic-CLP); Sequence variation: Gene deletion; TP53; Zygosity=Homozygous (PubMed=2858093)
Groups: Group: Space-flown cell line (cellonaut); Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: ENCODE project common cell types; tier 3; Part of: LL-100 blood cancer cell line panel; Part of: MD Anderson Cell Lines Project; Part of: MYC genetic alteration cell panel (ATCC TCP-1035); Registration: National Institute of Standards and Technology, Standard Reference Materials; SRM 2392-I
Description: Genome ancestry: African=1.15%; Native American=0.42%; East Asian, North=0.4%; East Asian, South=0%; South Asian=0%; European, North=71.71%; European, South=26.32% (PubMed=30894373)
Child Cell Lines: CVCL_0304 (HL-60/ADR)
CVCL_0305 (HL-60/VCR)
CVCL_0478 (P39)
CVCL_2162 (PLB-985)
CVCL_2493 (HL-60 clone 15)
CVCL_2495 (HL60 Ast.3)
CVCL_2496 (HL60 Ast.4)
CVCL_2497 (HL60 M2)
CVCL_2498 (HL60 M4)
CVCL_2892 (Eos-HL-60)
CVCL_2944 (HL60(S))
CVCL_2945 (HL60RG)
CVCL_3332 (HL-60/MX1)
CVCL_4458 (HL-60/DNR)
CVCL_4635 (HL-60-R2)
CVCL_4967 (HL-60/Vinc)
CVCL_4V19 (HL-60/ara-C [Japan 2011])
CVCL_4V55 (HL/CAFdA20)
CVCL_8439 (HIMeg-1)
CVCL_8710 (HP100-1)
CVCL_8711 (HP50-2)
CVCL_8907 (RED-3)
CVCL_8931 (YJ)
CVCL_A4BY (HL-60-Luc2)
CVCL_A794 (HL-60(TB))
CVCL_AR85 (HL60 Ast.25)
CVCL_AR88 (HL60 Ast.1)
CVCL_AR89 (HL60 Sp1)
CVCL_D567 (OM10.1)
CVCL_II77 (HL-60/S4)
CVCL_II78 (HL-60/R3)
CVCL_IP18 (HL-60/AMSA)
CVCL_J128 (VXG3)
CVCL_J129 (XQH)
CVCL_RS49 (HL-60rARA-C2mug/ML)
CVCL_UM46 (HL-60 248)
CVCL_UM47 (HL-60 SCX3)
CVCL_UM48 (HL-60 SN3)
CVCL_VK43 (HL-60 blast)
CVCL_WI27 (HL60/AR)
CVCL_WR44 (HL-60/AR)
CVCL_WW75 (HL-60-Y3)
CVCL_WZ17 (HL-60 DeltaF508-CF)
CVCL_XE38 (HL-60/RS)
CVCL_YN03 (NDi001-A)
CVCL_YP33 (HL-60/5FU)
CVCL_YT56 (HL-60R)
CVCL_Z938 (HL-60/ara-C [USA 1984])
Aliases: HL 60; HL.60 HL60; HL60; IIL-60

References
Additional References at PubMed
PMID:271272   PMID:288488   PMID:1574572   PMID:1970118   PMID:2140233   PMID:2545346   PMID:2858093   PMID:3335022   PMID:3422031   PMID:3860286   PMID:6091813   PMID:6255959  
PMID:6582512   PMID:6945469   PMID:6954533   PMID:6996765   PMID:7630190   PMID:8316623   PMID:8343448   PMID:8558913   PMID:8562479   PMID:9434637   PMID:9510473   PMID:9557624  
PMID:9607592   PMID:9737686   PMID:9738977   PMID:12068308   PMID:12661003   PMID:15843827   PMID:16120335   PMID:16408098   PMID:17088437   PMID:20164919   PMID:20215515   PMID:22068913  
PMID:22460905   PMID:22944676   PMID:23955599   PMID:24368162   PMID:24670534   PMID:25485619   PMID:25894527   PMID:25984343   PMID:27397505   PMID:28109323   PMID:28196595   PMID:30285677  
PMID:30670178   PMID:30894373   PMID:31068700   PMID:31160637  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-38 CELLOSAURUS
  E-MTAB-7721 CELLOSAURUS
  E-MTAB-7722 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
ATCC CCL-240 CELLOSAURUS
BCRC 60027 CELLOSAURUS
BCRJ 0104 CELLOSAURUS
BioSample SAMN01821559 CELLOSAURUS
  SAMN01821682 CELLOSAURUS
  SAMN03472768 CELLOSAURUS
  SAMN03473174 CELLOSAURUS
  SAMN10988245 CELLOSAURUS
BTO BTO_0000738 CELLOSAURUS
CCRID 3111C0001CCC000037 CELLOSAURUS
  3111C0002000000098 CELLOSAURUS
  3131C0001000700023 CELLOSAURUS
  3142C0001000000027 CELLOSAURUS
  3142C0001000000028 CELLOSAURUS
Cell Line Ontology CLO_0003775 CELLOSAURUS
  CLO_0050972 CELLOSAURUS
Cell Model Passports SIDM00829 CELLOSAURUS
Cellosaurus CVCL_0002 CELLOSAURUS
ChEMBL-Cells CHEMBL3307654 CELLOSAURUS
ChEMBL-Targets CHEMBL383 CELLOSAURUS
COSMIC Samples 1012068 CELLOSAURUS
  1019836 CELLOSAURUS
  1037661 CELLOSAURUS
  1070693 CELLOSAURUS
  1078724 CELLOSAURUS
  1089519 CELLOSAURUS
  1092602 CELLOSAURUS
  1107177 CELLOSAURUS
  1127250 CELLOSAURUS
  1130234 CELLOSAURUS
  1168468 CELLOSAURUS
  1176580 CELLOSAURUS
  1181599 CELLOSAURUS
  1191695 CELLOSAURUS
  1192826 CELLOSAURUS
  1226863 CELLOSAURUS
  1281315 CELLOSAURUS
  1305337 CELLOSAURUS
  1308224 CELLOSAURUS
  1319549 CELLOSAURUS
  1451845 CELLOSAURUS
  1465966 CELLOSAURUS
  1523825 CELLOSAURUS
  1524830 CELLOSAURUS
  1582390 CELLOSAURUS
  1601062 CELLOSAURUS
  1604861 CELLOSAURUS
  1998444 CELLOSAURUS
  2036678 CELLOSAURUS
  2089652 CELLOSAURUS
  2131539 CELLOSAURUS
  2301565 CELLOSAURUS
  2306208 CELLOSAURUS
  2651387 CELLOSAURUS
  716179 CELLOSAURUS
  716190 CELLOSAURUS
  724817 CELLOSAURUS
  787433 CELLOSAURUS
  798224 CELLOSAURUS
  798665 CELLOSAURUS
  808506 CELLOSAURUS
  821043 CELLOSAURUS
  850380 CELLOSAURUS
  851996 CELLOSAURUS
  875866 CELLOSAURUS
  905938 CELLOSAURUS
  919116 CELLOSAURUS
  922161 CELLOSAURUS
  922683 CELLOSAURUS
  924049 CELLOSAURUS
  932769 CELLOSAURUS
  947366 CELLOSAURUS
  949099 CELLOSAURUS
  975252 CELLOSAURUS
  981578 CELLOSAURUS
  991557 CELLOSAURUS
  994170 CELLOSAURUS
  999724 CELLOSAURUS
Cosmic-CLP 905938 CELLOSAURUS
DepMap ACH-000002 CELLOSAURUS
DOI 10.1016/B978-0-12-221970-2.50457-5 CELLOSAURUS
  10.1159/000415060 CELLOSAURUS
DSMZ ACC-3 CELLOSAURUS
ECACC 98070106 CELLOSAURUS
EFO EFO_0002793 CELLOSAURUS
ENCODE ENCBS069ENC CELLOSAURUS
  ENCBS070ENC CELLOSAURUS
  ENCBS215JQI CELLOSAURUS
  ENCBS308XSW CELLOSAURUS
  ENCBS373UEY CELLOSAURUS
  ENCBS482VCU CELLOSAURUS
  ENCBS698WLF CELLOSAURUS
  ENCBS869DKF CELLOSAURUS
  ENCBS880XNW CELLOSAURUS
GDSC 905938 CELLOSAURUS
GEO GSM1153417 CELLOSAURUS
  GSM1181331 CELLOSAURUS
  GSM1181348 CELLOSAURUS
  GSM1374535 CELLOSAURUS
  GSM1374536 CELLOSAURUS
  GSM1446736 CELLOSAURUS
  GSM1669883 CELLOSAURUS
  GSM213809 CELLOSAURUS
  GSM236782 CELLOSAURUS
  GSM236818 CELLOSAURUS
  GSM472908 CELLOSAURUS
  GSM472942 CELLOSAURUS
  GSM482507 CELLOSAURUS
  GSM50194 CELLOSAURUS
  GSM50258 CELLOSAURUS
  GSM545496 CELLOSAURUS
  GSM545497 CELLOSAURUS
  GSM743458 CELLOSAURUS
  GSM750812 CELLOSAURUS
  GSM799346 CELLOSAURUS
  GSM799409 CELLOSAURUS
  GSM887083 CELLOSAURUS
  GSM888153 CELLOSAURUS
  GSM945222 CELLOSAURUS
  GSM945255 CELLOSAURUS
ICLC HTL95010 CELLOSAURUS
IGRhCellID HL60 CELLOSAURUS
JCRB IFO50022 CELLOSAURUS
  JCRB0085 CELLOSAURUS
  NIHS0086 CELLOSAURUS
KCLB 10240 CELLOSAURUS
LiGeA CCLE_789 CELLOSAURUS
LINCS_LDP LCL-1054 CELLOSAURUS
Lonza 64 CELLOSAURUS
MESH D018922 CELLOSAURUS
NCIt C9154 CELLOSAURUS
Orphanet 519 CELLOSAURUS
PharmacoDB HL60_546_2019 CELLOSAURUS
PRIDE PRD000345 CELLOSAURUS
  PXD000589 CELLOSAURUS
  PXD006421 CELLOSAURUS
Progenetix CVCL_0002 CELLOSAURUS
RCB RCB0041 CELLOSAURUS
  RCB3683 CELLOSAURUS
Wikidata Q5630035 CELLOSAURUS