CVCL_0039 - Rat Genome Database

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Cell Line : CVCL_0039 (SK-MEL-30) Homo sapiens

Symbol: CVCL_0039
Name: SK-MEL-30
RGD ID: 21113420
Cell Line Type: cancer cell line
Gender: Male
Source: From: Memorial Sloan Kettering Cancer Center; New York; USA
Research Use: Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep quantitative proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: SNP array analysis; Omics: Transcriptome analysis
Characteristics: Characteristics: Pigmented
Phenotype: Doubling time: ~30 hours (DSMZ); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Heterozygous for APC p.Gly1339Arg (c.4015G>C) (ClinVar=VCV000233611) (CCLE; Cosmic-CLP); Sequence variation: Heterozygous for APC p.Gln1406Ter (c.4216C>T) (ClinVar=VCV000142519) (CCLE; Cosmic-CLP); Sequence variation: Homozygous for CDKN2A p.Pro114Leu (c.341C>T) (p.Ala128Ala; c.384C>T) (ClinVar=VCV000077637) (CCLE; Cosmic-CLP); Sequence variation: Heterozygous for NRAS p.Gln61Lys (c.181C>A) (ClinVar=VCV000073058) (PubMed=10766161; PubMed=21725359; PubMed=24576830; CCLE; Cosmic-CLP); Sequence variation: TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (PubMed=31068700); Sequence variation: Heterozygous for TP53 p.Thr284fs*21 (c.851_852delCA) (p.R283fs; c.849_850del2) (CCLE; Cosmic-CLP)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK1980-526
Description: Genome ancestry: African=0%; Native American=0%; East Asian, North=1.6%; East Asian, South=0%; South Asian=0%; European, North=62.41%; European, South=35.99% (PubMed=30894373).
Aliases: AW-Mel; SK Mel 30; Sk Mel30; SK-Mel-30; SKMEL-30
Disease(s): skin melanoma (DOID:8923) [NCI:C3510]

References
Additional References at PubMed
PMID:978138   PMID:1067619   PMID:1716514   PMID:3081645   PMID:3473501   PMID:3518877   PMID:6864164   PMID:6933476   PMID:7175440   PMID:7509835   PMID:10766161   PMID:15009714  
PMID:20164919   PMID:21725359   PMID:22460905   PMID:24576830   PMID:25485619   PMID:27397505   PMID:30894373   PMID:31068700   PMID:31978347  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
BioSample SAMN03473251 CELLOSAURUS
  SAMN10988313 CELLOSAURUS
BTO BTO_0002133 CELLOSAURUS
Cell Line Ontology CLO_0009045 CELLOSAURUS
Cell Model Passports SIDM00392 CELLOSAURUS
Cellosaurus CVCL_0039 CELLOSAURUS
ChEMBL-Cells CHEMBL3308128 CELLOSAURUS
ChEMBL-Targets CHEMBL1075577 CELLOSAURUS
COSMIC Samples 1022283 CELLOSAURUS
  1060425 CELLOSAURUS
  1669146 CELLOSAURUS
  706090 CELLOSAURUS
  721825 CELLOSAURUS
  851035 CELLOSAURUS
  888061 CELLOSAURUS
  888834 CELLOSAURUS
  909726 CELLOSAURUS
  933128 CELLOSAURUS
Cosmic-CLP 909726 CELLOSAURUS
DepMap ACH-000810 CELLOSAURUS
DOI 10.1007/978-1-4615-7228-2_39 CELLOSAURUS
DSMZ ACC-151 CELLOSAURUS
EFO EFO_0006488 CELLOSAURUS
GDSC 909726 CELLOSAURUS
GEO GSM1670441 CELLOSAURUS
  GSM784510 CELLOSAURUS
  GSM887586 CELLOSAURUS
  GSM888669 CELLOSAURUS
LiGeA CCLE_671 CELLOSAURUS
LINCS_LDP LCL-1257 CELLOSAURUS
NCIt C3510 CELLOSAURUS
PharmacoDB SKMEL30_1398_2019 CELLOSAURUS
Progenetix CVCL_0039 CELLOSAURUS
Wikidata Q54954059 CELLOSAURUS