CVCL_0036 - Rat Genome Database

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Cell Line : CVCL_0036 (RT-4) Homo sapiens

Symbol: CVCL_0036
Name: RT-4
RGD ID: 21113419
Cell Line Type: cancer cell line
Gender: Male
Research Use: Omics: CNV analysis; Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep quantitative proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: SNP array analysis; Omics: Transcriptome analysis
Availability: Discontinued: ATCC; CRL-7937; true.
Phenotype: Doubling time: 37 hours (PubMed=3708594); 65.8 hours (PubMed=26055179); ~80 hours (DSMZ); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Gene fusion; FGFR3-TACC3 (PubMed=28855393); Sequence variation: Gene deletion; CDKN2A; Zygosity=Homozygous (PubMed=9850064); Sequence variation: TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (PubMed=24035680); Sequence variation: Mutation; TP53; none detected (PubMed=7787250)
Groups: Part of: BLA-40 bladder carcinoma cell line panel; Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: ERK genetic alteration cell panel (ATCC TCP-1033); Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982); Part of: TCGA-110-CL cell line panel; Part of: UBC-40 urothelial bladder cancer cell line index
Description: HLA typing: A*03:01,02:01; B*44:02,44:02; C*05:01,05:01; DQA1*03:02,03:02; DQB1*05:03,05:03 (PubMed=25960936); Genome ancestry: African=0%; Native American=0%; East Asian, North=2.72%; East Asian, South=0%; South Asian=0.98%; European, North=64.69%; European, South=31.61% (PubMed=30894373)
Child Cell Lines: CVCL_2715 (RT4/31)
CVCL_RR19 (RT4rCDDP1000)
CVCL_RR20 (RT4rGEMCI10)
CVCL_T027 (RT4v6)
Aliases: RT4; RT4P
Disease(s): bladder carcinoma (DOID:4007) [NCI:C4912]

References
Additional References at PubMed
PMID:327080   PMID:571047   PMID:833871   PMID:864752   PMID:870558   PMID:1114348   PMID:3518877   PMID:3708594   PMID:5503601   PMID:6220172   PMID:6244232   PMID:6582512  
PMID:6823318   PMID:7017212   PMID:7459858   PMID:7787250   PMID:8873383   PMID:9850064   PMID:11207054   PMID:11921286   PMID:15846775   PMID:16885334   PMID:20164919   PMID:20215515  
PMID:22460905   PMID:23401075   PMID:24018021   PMID:24035680   PMID:24367658   PMID:25485619   PMID:25960936   PMID:25997541   PMID:26055179   PMID:27270441   PMID:27397505   PMID:28855393  
PMID:29732388   PMID:30894373   PMID:31068700   PMID:31395879   PMID:31978347  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
ATCC CRL-7937 CELLOSAURUS
  HTB-2 CELLOSAURUS
BCRC 60111 CELLOSAURUS
BCRJ 0214 CELLOSAURUS
BioSample SAMN03473092 CELLOSAURUS
  SAMN10988330 CELLOSAURUS
BTO BTO_0002870 CELLOSAURUS
CCRID 3131C0001001200015 CELLOSAURUS
  3153C0001000000253 CELLOSAURUS
Cell Line Ontology CLO_0008892 CELLOSAURUS
Cell Model Passports SIDM01085 CELLOSAURUS
Cellosaurus CVCL_0036 CELLOSAURUS
ChEMBL-Cells CHEMBL3307430 CELLOSAURUS
ChEMBL-Targets CHEMBL614884 CELLOSAURUS
COSMIC Samples 1016881 CELLOSAURUS
  1046681 CELLOSAURUS
  1068091 CELLOSAURUS
  1285125 CELLOSAURUS
  1285983 CELLOSAURUS
  1819325 CELLOSAURUS
  1927301 CELLOSAURUS
  2037955 CELLOSAURUS
  2050460 CELLOSAURUS
  2057455 CELLOSAURUS
  2444250 CELLOSAURUS
  2686112 CELLOSAURUS
  2700996 CELLOSAURUS
  687455 CELLOSAURUS
  715805 CELLOSAURUS
  755396 CELLOSAURUS
  760479 CELLOSAURUS
  845560 CELLOSAURUS
  846283 CELLOSAURUS
  867839 CELLOSAURUS
  925819 CELLOSAURUS
  928816 CELLOSAURUS
  943749 CELLOSAURUS
Cosmic-CLP 687455 CELLOSAURUS
DepMap ACH-000242 CELLOSAURUS
DSMZ ACC-412 CELLOSAURUS
ECACC 91091914 CELLOSAURUS
EFO EFO_0006480 CELLOSAURUS
GDSC 687455 CELLOSAURUS
GEO GSM136232 CELLOSAURUS
  GSM1374859 CELLOSAURUS
  GSM1574570 CELLOSAURUS
  GSM1670394 CELLOSAURUS
  GSM763024 CELLOSAURUS
  GSM827439 CELLOSAURUS
  GSM887553 CELLOSAURUS
  GSM888636 CELLOSAURUS
KCLB 30002 CELLOSAURUS
LiGeA CCLE_210 CELLOSAURUS
LINCS_LDP LCL-1717 CELLOSAURUS
NCIt C4912 CELLOSAURUS
PharmacoDB RT4_1334_2019 CELLOSAURUS
Progenetix CVCL_0036 CELLOSAURUS
Wikidata Q54951351 CELLOSAURUS