CVCL_0037 - Rat Genome Database

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Cell Line : CVCL_0037 (A-431) Homo sapiens

Symbol: CVCL_0037
Name: A-431
RGD ID: 21113418
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Skin; epidermis.
Gender: Female
Research Use: Omics: Cell surface proteome; Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep phosphoproteome analysis; Omics: Deep proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: SNP array analysis; Omics: Transcriptome analysis
Availability: Discontinued: ATCC; CRL-7907; true
Phenotype: Doubling time: ~80-100 hours (DSMZ); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Gene fusion; EGFR-PPARGC1A (PubMed=23637631); Sequence variation: TP53 p.Arg273His (c.818G>A) (ClinVar=VCV000012366) (PubMed=1394225)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)
Description: HLA typing: A*03:01,03:01; B*07:02,07:02; C*07:02,07:02 (PubMed=25960936); Genome ancestry: African=3.82%; Native American=0%; East Asian, North=7.84%; East Asian, South=0%; South Asian=6.03%; European, North=17.15%; European, South=65.16% (PubMed=30894373)
Child Cell Lines: CVCL_3485 (A431NS)
CVCL_4V41 (A431/TPT)
CVCL_EQ67 (A431-PR)
CVCL_GY97 (A431/CDDP1)
CVCL_GY98 (A431/CDDP2)
CVCL_QX11 (A431 siYAP)
CVCL_QX12 (A431 YAP-5SA)
CVCL_WS72 (A431PF)
Aliases: A431; A431/P
Disease(s): skin squamous cell carcinoma (DOID:3151) [NCI:C4819]

References
Additional References at PubMed
PMID:212188   PMID:1394225   PMID:2228902   PMID:2758419   PMID:2990217   PMID:4357758   PMID:6092175   PMID:6254071   PMID:6500159   PMID:6954533   PMID:9290701   PMID:9887230  
PMID:17178626   PMID:20164919   PMID:20215515   PMID:22108792   PMID:22282976   PMID:23637631   PMID:24804581   PMID:25485619   PMID:25894527   PMID:25960936   PMID:26989177   PMID:27397505  
PMID:28176443   PMID:30894373  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
ATCC CRL-1555 CELLOSAURUS
  CRL-7907 CELLOSAURUS
BCRC 60161 CELLOSAURUS
BCRJ 0032 CELLOSAURUS
BioSample SAMN01821614 CELLOSAURUS
  SAMN01821671 CELLOSAURUS
  SAMN01821724 CELLOSAURUS
  SAMN03472220 CELLOSAURUS
BTO BTO_0000017 CELLOSAURUS
CCRID 3111C0001CCC000092 CELLOSAURUS
  3131C0001000700079 CELLOSAURUS
  3131C0001000700188 CELLOSAURUS
  3142C0001000000103 CELLOSAURUS
Cell Line Ontology CLO_0001591 CELLOSAURUS
  CLO_0001592 CELLOSAURUS
  CLO_0050011 CELLOSAURUS
  CLO_0050012 CELLOSAURUS
Cell Model Passports SIDM00995 CELLOSAURUS
Cellosaurus CVCL_0037 CELLOSAURUS
ChEMBL-Cells CHEMBL3307523 CELLOSAURUS
ChEMBL-Targets CHEMBL614069 CELLOSAURUS
COSMIC Samples 1071898 CELLOSAURUS
  1176624 CELLOSAURUS
  1351516 CELLOSAURUS
  1477434 CELLOSAURUS
  1945879 CELLOSAURUS
  1995334 CELLOSAURUS
  2131571 CELLOSAURUS
  2301592 CELLOSAURUS
  2646654 CELLOSAURUS
  688038 CELLOSAURUS
  735609 CELLOSAURUS
  755305 CELLOSAURUS
  876559 CELLOSAURUS
  897743 CELLOSAURUS
  910564 CELLOSAURUS
  910925 CELLOSAURUS
  974317 CELLOSAURUS
Cosmic-CLP 910925 CELLOSAURUS
DepMap ACH-001328 CELLOSAURUS
DSMZ ACC-91 CELLOSAURUS
ECACC 85090402 CELLOSAURUS
EFO EFO_0006268 CELLOSAURUS
GDSC 910925 CELLOSAURUS
GEO GSM1374384 CELLOSAURUS
  GSM1669586 CELLOSAURUS
  GSM183432 CELLOSAURUS
  GSM183433 CELLOSAURUS
  GSM2112551 CELLOSAURUS
  GSM2112555 CELLOSAURUS
  GSM827302 CELLOSAURUS
JCRB IFO50411 CELLOSAURUS
  JCRB0004 CELLOSAURUS
  JCRB9009 CELLOSAURUS
KCLB 21555 CELLOSAURUS
  80005 CELLOSAURUS
LINCS_LDP LCL-1404 CELLOSAURUS
Lonza 814 CELLOSAURUS
NCIt C4819 CELLOSAURUS
PharmacoDB A431_46_2019 CELLOSAURUS
PRIDE PXD000065 CELLOSAURUS
  PXD000589 CELLOSAURUS
  PXD000681 CELLOSAURUS
  PXD001582 CELLOSAURUS
  PXD003937 CELLOSAURUS
  PXD005301 CELLOSAURUS
  PXD006291 CELLOSAURUS
  PXD007206 CELLOSAURUS
  PXD008996 CELLOSAURUS
Progenetix CVCL_0037 CELLOSAURUS
RCB RCB0202 CELLOSAURUS
  RCB1872 CELLOSAURUS
Wikidata Q4649310 CELLOSAURUS