CVCL_0035 - Rat Genome Database

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Cell Line : CVCL_0035 (PC-3) Homo sapiens

Symbol: CVCL_0035
Name: PC-3
RGD ID: 21113416
Cell Line Type: cancer cell line
Origin: Population: Caucasian; Derived from metastatic site: Bone.
Gender: Male
Research Use: Omics: Array-based CGH; Omics: CNV analysis; Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep proteome analysis; Omics: Deep quantitative proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: Fluorescence phenotype profiling; Omics: Glycoproteome analysis by proteomics; Omics: GPI-anchored proteins analysis by proteomics; Omics: lncRNA expression profiling; Omics: Metabolome analysis; Omics: Protein expression by reverse-phase protein arrays; Omics: Secretome proteome analysis; Omics: SNP array analysis; Omics: Transcriptome analysis
Availability: Discontinued: ATCC; CRL-7934; true
Phenotype: Doubling time: 25.34 +- 0.02 hours (PubMed=32968452); 27.1 hours (NCI-DTP); 25 hours (ATCC); ~50 hours (DSMZ); ~25 hours (PBCF); 40 +- 10 hours (CLS); Microsatellite instability: Stable (MSS) (PubMed=23671654; Sanger)
Genomic Alteration: Sequence variation: Homozygous for TP53 p.Lys139Argfs*31 (c.414delC) (413delC) (ClinVar=VCV000133281) (PubMed=1873816; PubMed=8104329; PubMed=17088437; Cosmic-CLP; CCLE)
Caution: Caution: There seems to be two distinct cell lines which were assigned NCBI_Iran catalog number C427
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: JFCR39 cancer cell line panel; Part of: MD Anderson Cell Lines Project; Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982); Part of: NCI-60 cancer cell line panel
Description: HLA typing: A*01:01:01,24:02:01; B*13:02,55:01; C*01,06; DPB1*04:01; DQB1*02:02,06:03; DRB1*07:01,13:01:01 (PubMed=15748285); HLA typing: A*01:01,24:01; B*13:02,55:01; C*06:02,01:02 (PubMed=25960936); Genome ancestry: African=0.41%; Native American=0%; East Asian, North=0.52%; East Asian, South=0%; South Asian=1.19%; European, North=65.73%; European, South=32.14% (PubMed=30894373)
Child Cell Lines: CVCL_0482 (PC-3U)
CVCL_4734 (ALVA-41)
CVCL_4735 (ALVA-101)
CVCL_4736 (ALVA-55)
CVCL_4737 (ALVA-31)
CVCL_4738 (DuPro-1)
CVCL_4778 (PPC-1)
CVCL_4868 (MPC-3-10)
CVCL_4877 (PC-3-1A)
CVCL_4886 (PC-3N)
CVCL_4Y40 (PC-3 D12)
CVCL_4Y41 (PC-3 D8)
CVCL_5989 (JHU-019)
CVCL_5J08 (PC-3-Red-FLuc)
CVCL_5J09 (PC-3-Red-FLuc-GFP)
CVCL_5J26 (PC-3-luc2)
CVCL_5J29 (PC-3-luc2-GFP)
CVCL_6E88 (PC-3 MC)
CVCL_6E89 (PC-3 MK)
CVCL_6E90 (PC-3 ML)
CVCL_6E91 (PC-3 MR)
CVCL_9555 (PC-3M)
CVCL_A2FD (PC-3/DTX)
CVCL_A4BV (PC-3-Luc2)
CVCL_B289 (PC-3H)
CVCL_C169 (PCI-03)
CVCL_D689 (PC3B1)
CVCL_J265 (PC-3-Luc)
CVCL_L211 (1-LN)
CVCL_M060 (PC-3/nKR)
CVCL_M124 (PC-5 [Human prostate carcinoma])
CVCL_RS41 (PC-3rYM155_20nM)
CVCL_RS45 (PC-3rVCR20)
CVCL_WM76 (PC3-R-caba)
CVCL_X641 (PC-J)
CVCL_XD72 (PC-3-Cas9-576)
CVCL_XD73 (PC-3-Cas9-577)
CVCL_XD74 (PC-3-Cas9-578)
CVCL_XD75 (PC-3-Cas9-579)
CVCL_YJ69 (VAMPIRO PC-3)
CVCL_YJ90 (LINTERNA PC-3)
CVCL_ZX05 (PC-3-TxR)
Aliases: PC.3; PC3
Disease(s): prostate carcinoma (DOID:10286) [NCI:C4863]

References
Additional References at PubMed
PMID:447482   PMID:571045   PMID:1873816   PMID:3335022   PMID:3518877   PMID:6244232   PMID:8104329   PMID:8687134   PMID:9018337   PMID:9823299   PMID:10700174   PMID:10702678  
PMID:10754530   PMID:10972993   PMID:11135431   PMID:11172901   PMID:11414198   PMID:12725112   PMID:14518029   PMID:15486987   PMID:15748285   PMID:17088437   PMID:17254797   PMID:17440963  
PMID:19372543   PMID:20164919   PMID:21432867   PMID:22068913   PMID:22275356   PMID:22336246   PMID:22384151   PMID:22460905   PMID:22628656   PMID:23671654   PMID:23856246   PMID:23933261  
PMID:24279929   PMID:24504141   PMID:24670534   PMID:25485619   PMID:25960936   PMID:26256267   PMID:26972028   PMID:27141528   PMID:27377824   PMID:27397505   PMID:27807467   PMID:28196595  
PMID:30787054   PMID:30894373   PMID:31068700   PMID:31404090   PMID:31978347   PMID:32968452  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
ATCC CRL-1435 CELLOSAURUS
  CRL-7934 CELLOSAURUS
BCRC 60122 CELLOSAURUS
BCRJ 0269 CELLOSAURUS
BioSample SAMN01821588 CELLOSAURUS
  SAMN01821653 CELLOSAURUS
  SAMN01821713 CELLOSAURUS
  SAMN03472063 CELLOSAURUS
  SAMN05292438 CELLOSAURUS
  SAMN10988356 CELLOSAURUS
BTO BTO_0001061 CELLOSAURUS
CCRID 3111C0001CCC000115 CELLOSAURUS
  3131C0001000700041 CELLOSAURUS
  3131C0001000700158 CELLOSAURUS
  3142C0001000000113 CELLOSAURUS
Cell Line Ontology CLO_0008395 CELLOSAURUS
  CLO_0051535 CELLOSAURUS
Cell Model Passports SIDM00088 CELLOSAURUS
Cellosaurus CVCL_0035 CELLOSAURUS
ChEMBL-Cells CHEMBL3307570 CELLOSAURUS
ChEMBL-Targets CHEMBL390 CELLOSAURUS
COSMIC Samples 1028650 CELLOSAURUS
  1028702 CELLOSAURUS
  1071477 CELLOSAURUS
  1075273 CELLOSAURUS
  1092627 CELLOSAURUS
  1172628 CELLOSAURUS
  1175888 CELLOSAURUS
  1188436 CELLOSAURUS
  1212489 CELLOSAURUS
  1219448 CELLOSAURUS
  1305380 CELLOSAURUS
  1312367 CELLOSAURUS
  1330910 CELLOSAURUS
  1436048 CELLOSAURUS
  1689714 CELLOSAURUS
  1995613 CELLOSAURUS
  1998469 CELLOSAURUS
  2301588 CELLOSAURUS
  2580130 CELLOSAURUS
  2585153 CELLOSAURUS
  2585230 CELLOSAURUS
  2621167 CELLOSAURUS
  2651772 CELLOSAURUS
  2669172 CELLOSAURUS
  2674178 CELLOSAURUS
  688118 CELLOSAURUS
  704849 CELLOSAURUS
  713868 CELLOSAURUS
  719680 CELLOSAURUS
  721366 CELLOSAURUS
  721556 CELLOSAURUS
  755297 CELLOSAURUS
  759894 CELLOSAURUS
  801350 CELLOSAURUS
  809225 CELLOSAURUS
  850414 CELLOSAURUS
  869157 CELLOSAURUS
  873002 CELLOSAURUS
  875892 CELLOSAURUS
  876396 CELLOSAURUS
  897455 CELLOSAURUS
  905934 CELLOSAURUS
  911997 CELLOSAURUS
  918502 CELLOSAURUS
  920968 CELLOSAURUS
  921048 CELLOSAURUS
  922551 CELLOSAURUS
  923957 CELLOSAURUS
  943175 CELLOSAURUS
  948379 CELLOSAURUS
  949249 CELLOSAURUS
  974299 CELLOSAURUS
Cosmic-CLP 905934 CELLOSAURUS
DepMap ACH-000090 CELLOSAURUS
DOI 10.4172/2157-7145.S2-005 CELLOSAURUS
DSMZ ACC-465 CELLOSAURUS
ECACC 90112714 CELLOSAURUS
EFO EFO_0002074 CELLOSAURUS
ENCODE ENCBS420VDY CELLOSAURUS
  ENCBS451OVM CELLOSAURUS
  ENCBS504WVV CELLOSAURUS
  ENCBS596CTT CELLOSAURUS
  ENCBS608AAA CELLOSAURUS
  ENCBS609AAA CELLOSAURUS
GDSC 905934 CELLOSAURUS
GEO GSM1153442 CELLOSAURUS
  GSM1178542 CELLOSAURUS
  GSM1178543 CELLOSAURUS
  GSM1181274 CELLOSAURUS
  GSM1181303 CELLOSAURUS
  GSM1374817 CELLOSAURUS
  GSM1374818 CELLOSAURUS
  GSM142459 CELLOSAURUS
  GSM142460 CELLOSAURUS
  GSM1670339 CELLOSAURUS
  GSM2124647 CELLOSAURUS
  GSM2171 CELLOSAURUS
  GSM482670 CELLOSAURUS
  GSM50225 CELLOSAURUS
  GSM50289 CELLOSAURUS
  GSM525804 CELLOSAURUS
  GSM595615 CELLOSAURUS
  GSM648823 CELLOSAURUS
  GSM743480 CELLOSAURUS
  GSM750835 CELLOSAURUS
  GSM784792 CELLOSAURUS
  GSM799370 CELLOSAURUS
  GSM799433 CELLOSAURUS
  GSM844674 CELLOSAURUS
  GSM844675 CELLOSAURUS
  GSM847110 CELLOSAURUS
  GSM887506 CELLOSAURUS
  GSM888588 CELLOSAURUS
  GSM91930 CELLOSAURUS
ICLC HTL97018 CELLOSAURUS
JCRB JCRB9110 CELLOSAURUS
KCLB 21435 CELLOSAURUS
LiGeA CCLE_525 CELLOSAURUS
LINCS_HMS 50454 CELLOSAURUS
LINCS_LDP LCL-1299 CELLOSAURUS
Lonza 125 CELLOSAURUS
NCIt C4863 CELLOSAURUS
PharmacoDB PC3_1248_2019 CELLOSAURUS
PRIDE PRD000228 CELLOSAURUS
  PRD000597 CELLOSAURUS
  PXD000661 CELLOSAURUS
  PXD002107 CELLOSAURUS
  PXD003105 CELLOSAURUS
  PXD005940 CELLOSAURUS
  PXD005942 CELLOSAURUS
  PXD008184 CELLOSAURUS
Progenetix CVCL_0035 CELLOSAURUS
RCB RCB2145 CELLOSAURUS
Wikidata Q7118483 CELLOSAURUS