CVCL_0033 - Rat Genome Database

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Cell Line : CVCL_0033 (SK-BR-3) Homo sapiens

Symbol: CVCL_0033
Name: SK-BR-3
RGD ID: 21113414
Cell Line Type: cancer cell line
Origin: Derived from metastatic site: Pleural effusion.
Gender: Female
Source: From: Memorial Sloan Kettering Cancer Center; New York; USA
Research Use: Omics: Array-based CGH; Omics: CNV analysis; Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep proteome analysis; Omics: Deep RNAseq analysis; Omics: Exosome proteome analysis; Omics: Genome sequenced; Omics: Glycoproteome analysis by proteomics; Omics: miRNA expression profiling; Omics: N-glycan profiling; Omics: Protein expression by reverse-phase protein arrays; Omics: SNP array analysis; Omics: Transcriptome analysis
Availability: Discontinued: RCB; RCB2132; true; Discontinued: TKG; TKG 0592; true
Phenotype: Doubling time: ~30 hours (CLS); ~2-3 days (DSMZ); 56.19 hours (https://www.synapse.org/#!Synapse:syn2347014); Microsatellite instability: Stable (MSS) (PubMed=23671654)
Genomic Alteration: Sequence variation: Gene deletion; CDH1; Zygosity=Homozygous (PubMed=19593635); Sequence variation: Homozygous for TP53 p.Arg175His (c.524G>A) (ClinVar=VCV000012374) (PubMed=16541312; PubMed=28889351; ATCC; CCLE)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: GrayJW breast cancer cell line panel; Part of: ICBP43 breast cancer cell line panel; Part of: KuDOS 95 cell line panel; Part of: MD Anderson Cell Lines Project; Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK 808
Description: HLA typing: A*02:01,02:01; B*14:02,39/50/55; C*03:04,03:04; DQB1*06:04,02:02 (PubMed=25960936); HLA typing: DPB1*03:01; DRB1*13:02 (IPD-IMGT/HLA; 12368); Genome ancestry: African=0.7%; Native American=0%; East Asian, North=2.13%; East Asian, South=0%; South Asian=0.26%; European, North=63.89%; European, South=33.02% (PubMed=30894373)
Child Cell Lines: CVCL_4V52 (SK-BR-3-LR)
CVCL_4V68 (SKBR3-LAP[r])
CVCL_4Y11 (SK-BR-3-Luc)
CVCL_A2FE (SKBR-3-OE)
CVCL_A2GI (LR-SKBR3)
CVCL_EI04 (SKBR3-AZDRa)
CVCL_EI05 (SKBR3-AZDRb)
CVCL_EI06 (SKBR3-AZDRc)
CVCL_EI07 (SKBR3-LAPRa)
CVCL_EI08 (SKBR3-LAPRb)
CVCL_EQ69 (SKBR3-PR)
CVCL_LG17 (SKBR3-LR)
CVCL_LG18 (SKBR3-NR)
CVCL_LG19 (SKBR3-TR)
CVCL_RA92 (SK-BR-3 shPARG)
CVCL_YJ28 (SK-BR-3 shWDR12-4)
CVCL_YJ71 (VAMPIRO SK-BR-3)
CVCL_YJ92 (LINTERNA SK-BR-3)
CVCL_YX81 (SKBR3 A3)
Originate from same individual as: CVCL_1074 (AU565)
Aliases: SK BR 03; SK-Br-3; SK-BR3; SKBR-3; SKBr3; SKBR3B
Disease(s): breast adenocarcinoma (DOID:3458) [NCI:C5214]

References
Additional References at PubMed
PMID:327080   PMID:833871   PMID:1013510   PMID:3518877   PMID:6401685   PMID:6500159   PMID:6582512   PMID:6935474   PMID:7017212   PMID:9671407   PMID:10862037   PMID:11044355  
PMID:12800145   PMID:15677628   PMID:16397213   PMID:16541312   PMID:17157791   PMID:18516279   PMID:19582160   PMID:19593635   PMID:19727395   PMID:20070913   PMID:20215515   PMID:21247443  
PMID:21378333   PMID:22460905   PMID:22585861   PMID:23151021   PMID:23601657   PMID:23671654   PMID:24009699   PMID:24094812   PMID:24162158   PMID:24176112   PMID:25485619   PMID:25960936  
PMID:26055192   PMID:26378940   PMID:28196595   PMID:28287265   PMID:28889351   PMID:29954844   PMID:30894373   PMID:31068700   PMID:32942617  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-TABM-157 CELLOSAURUS
  E-TABM-244 CELLOSAURUS
ATCC HTB-30 CELLOSAURUS
BCRJ 0226 CELLOSAURUS
BioSample SAMN01821597 CELLOSAURUS
  SAMN03471462 CELLOSAURUS
  SAMN10987910 CELLOSAURUS
BTO BTO_0002419 CELLOSAURUS
CCRID 3111C0001CCC000085 CELLOSAURUS
  3131C0001000700049 CELLOSAURUS
  3142C0001000000313 CELLOSAURUS
Cell Line Ontology CLO_0009034 CELLOSAURUS
  CLO_0037295 CELLOSAURUS
Cell Model Passports SIDM00897 CELLOSAURUS
CelloPub CLPUB00423 CELLOSAURUS
Cellosaurus CVCL_0033 CELLOSAURUS
ChEMBL-Cells CHEMBL3308062 CELLOSAURUS
ChEMBL-Targets CHEMBL613834 CELLOSAURUS
COSMIC Samples 1000127 CELLOSAURUS
  1010922 CELLOSAURUS
  1018478 CELLOSAURUS
  1044209 CELLOSAURUS
  1046958 CELLOSAURUS
  1129655 CELLOSAURUS
  1136357 CELLOSAURUS
  1176645 CELLOSAURUS
  1287914 CELLOSAURUS
  1289405 CELLOSAURUS
  1308997 CELLOSAURUS
  1434957 CELLOSAURUS
  1524342 CELLOSAURUS
  1571789 CELLOSAURUS
  1609462 CELLOSAURUS
  2036669 CELLOSAURUS
  2165013 CELLOSAURUS
  2301535 CELLOSAURUS
  2318379 CELLOSAURUS
  2361351 CELLOSAURUS
  687499 CELLOSAURUS
  755294 CELLOSAURUS
  759896 CELLOSAURUS
  871159 CELLOSAURUS
  894090 CELLOSAURUS
  897742 CELLOSAURUS
  904385 CELLOSAURUS
  921974 CELLOSAURUS
  923062 CELLOSAURUS
  934531 CELLOSAURUS
  944297 CELLOSAURUS
  979713 CELLOSAURUS
  991329 CELLOSAURUS
  997935 CELLOSAURUS
DepMap ACH-000017 CELLOSAURUS
DOI 10.1007/978-1-4757-1647-4_5 CELLOSAURUS
  10.1016/B978-0-12-333530-2.50009-5 CELLOSAURUS
DSMZ ACC-736 CELLOSAURUS
EFO EFO_0001236 CELLOSAURUS
GEO GSM1008913 CELLOSAURUS
  GSM1038850 CELLOSAURUS
  GSM1038851 CELLOSAURUS
  GSM1038852 CELLOSAURUS
  GSM1038853 CELLOSAURUS
  GSM1038854 CELLOSAURUS
  GSM1053720 CELLOSAURUS
  GSM115115 CELLOSAURUS
  GSM1172895 CELLOSAURUS
  GSM1172989 CELLOSAURUS
  GSM1214572 CELLOSAURUS
  GSM1238124 CELLOSAURUS
  GSM1264069 CELLOSAURUS
  GSM1264074 CELLOSAURUS
  GSM1264111 CELLOSAURUS
  GSM1264116 CELLOSAURUS
  GSM1374872 CELLOSAURUS
  GSM1374873 CELLOSAURUS
  GSM1374874 CELLOSAURUS
  GSM1401659 CELLOSAURUS
  GSM149978 CELLOSAURUS
  GSM149986 CELLOSAURUS
  GSM149994 CELLOSAURUS
  GSM152556 CELLOSAURUS
  GSM152557 CELLOSAURUS
  GSM152558 CELLOSAURUS
  GSM152559 CELLOSAURUS
  GSM154096 CELLOSAURUS
  GSM154097 CELLOSAURUS
  GSM154098 CELLOSAURUS
  GSM154099 CELLOSAURUS
  GSM154100 CELLOSAURUS
  GSM154101 CELLOSAURUS
  GSM154102 CELLOSAURUS
  GSM154104 CELLOSAURUS
  GSM154107 CELLOSAURUS
  GSM155215 CELLOSAURUS
  GSM1661988 CELLOSAURUS
  GSM170624 CELLOSAURUS
  GSM170625 CELLOSAURUS
  GSM170626 CELLOSAURUS
  GSM170627 CELLOSAURUS
  GSM170630 CELLOSAURUS
  GSM170631 CELLOSAURUS
  GSM170633 CELLOSAURUS
  GSM170634 CELLOSAURUS
  GSM1833627 CELLOSAURUS
  GSM183440 CELLOSAURUS
  GSM183441 CELLOSAURUS
  GSM186457 CELLOSAURUS
  GSM186458 CELLOSAURUS
  GSM217596 CELLOSAURUS
  GSM274644 CELLOSAURUS
  GSM274663 CELLOSAURUS
  GSM344357 CELLOSAURUS
  GSM344407 CELLOSAURUS
  GSM350501 CELLOSAURUS
  GSM378146 CELLOSAURUS
  GSM421883 CELLOSAURUS
  GSM481334 CELLOSAURUS
  GSM590106 CELLOSAURUS
  GSM595617 CELLOSAURUS
  GSM69195 CELLOSAURUS
  GSM73742 CELLOSAURUS
  GSM783927 CELLOSAURUS
  GSM827582 CELLOSAURUS
  GSM844686 CELLOSAURUS
  GSM844687 CELLOSAURUS
  GSM845399 CELLOSAURUS
  GSM847432 CELLOSAURUS
  GSM847499 CELLOSAURUS
  GSM887575 CELLOSAURUS
  GSM888658 CELLOSAURUS
ICLC HTL03005 CELLOSAURUS
IPD-IMGT/HLA 12368 CELLOSAURUS
KCLB 30030 CELLOSAURUS
LiGeA CCLE_391 CELLOSAURUS
LINCS_HMS 50057 CELLOSAURUS
LINCS_LDP LCL-1475 CELLOSAURUS
Lonza 70 CELLOSAURUS
NCIt C5214 CELLOSAURUS
PharmacoDB SKBR3_1383_2019 CELLOSAURUS
PRIDE PXD000691 CELLOSAURUS
  PXD002053 CELLOSAURUS
  PXD002057 CELLOSAURUS
  PXD002281 CELLOSAURUS
  PXD002486 CELLOSAURUS
  PXD005390 CELLOSAURUS
Progenetix CVCL_0033 CELLOSAURUS
RCB RCB2132 CELLOSAURUS
Wikidata Q7390592 CELLOSAURUS