CVCL_0040 - Rat Genome Database

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Cell Line : CVCL_0040 (WM115) Homo sapiens

Symbol: CVCL_0040
Name: WM115
RGD ID: 21113411
Cell Line Type: cancer cell line
Origin: Derived from metastatic site: Right anterior leg.
Gender: Female
Research Use: Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep quantitative proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: Protein expression by reverse-phase protein arrays; Omics: SNP array analysis; Omics: Transcriptome analysis
Availability: Discontinued: ATCC; CRL-1675; probable; Discontinued: Coriell; WC00079; probable; Discontinued: ECACC; 91061232; probable
Phenotype: Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Heterozygous for BRAF p.Val600Asp (c.1799_1800delTGinsAT) (ClinVar=VCV000375939) (PubMed=15467732; Wistar); Sequence variation: Gene deletion; PTEN; Zygosity=Hemizygous (Wistar)
Caution: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018; The major changes were: CSF1PO
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: MD Anderson Cell Lines Project; Part of: Wistar Institute melanoma cell line collection
Description: HLA typing: A*02:01,29:02; B*13:02,44:03:01; C*06:02,16:01; DPB1*02:01:02,02:01:02; DQB1*02:01,02:01; DRB1*07:01,07:01 (PubMed=15592718); Genome ancestry: African=0%; Native American=0.17%; East Asian, North=0%; East Asian, South=0%; South Asian=0.85%; European, North=67.47%; European, South=31.51% (PubMed=30894373)
Originate from same individual as: CVCL_2765 (WM266-4)
CVCL_6795 (WM239A)
CVCL_L033 (WM165-1)
CVCL_RN55 (WM165-2)
CVCL_RN56 (WM239B)
CVCL_RN57 (WM266-1)
CVCL_RN58 (WM266-2)
CVCL_RN59 (WM266-3)
Aliases: WC00079; WH115mel; WM 115; WM-115; WM115-mel; WM115F; WM115mel
Disease(s): melanoma (DOID:1909) [NCI:C3224]

References
Additional References at PubMed
PMID:2253310   PMID:3020539   PMID:3856042   PMID:4053039   PMID:15009714   PMID:15467732   PMID:15592718   PMID:16827748   PMID:18632627   PMID:20164919   PMID:20215515   PMID:21424129  
PMID:22460905   PMID:25485619   PMID:27397505   PMID:28196595   PMID:30894373   PMID:31068700   PMID:31978347  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-38 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
ATCC CRL-1675 CELLOSAURUS
BioSample SAMN10987773 CELLOSAURUS
BTO BTO_0003075 CELLOSAURUS
Cell Line Ontology CLO_0009613 CELLOSAURUS
Cell Model Passports SIDM01000 CELLOSAURUS
Cellosaurus CVCL_0040 CELLOSAURUS
ChEMBL-Cells CHEMBL3308813 CELLOSAURUS
ChEMBL-Targets CHEMBL1075611 CELLOSAURUS
Coriell WC00079 CELLOSAURUS
COSMIC Samples 1155268 CELLOSAURUS
  1155547 CELLOSAURUS
  1238102 CELLOSAURUS
  1238104 CELLOSAURUS
  886835 CELLOSAURUS
  888868 CELLOSAURUS
  897480 CELLOSAURUS
  905236 CELLOSAURUS
  909784 CELLOSAURUS
  932717 CELLOSAURUS
  972277 CELLOSAURUS
Cosmic-CLP 909784 CELLOSAURUS
DepMap ACH-000304 CELLOSAURUS
ECACC 91061232 CELLOSAURUS
EFO EFO_0002390 CELLOSAURUS
ESTDAB ESTDAB-066 CELLOSAURUS
GDSC 909784 CELLOSAURUS
GEO GSM109022 CELLOSAURUS
  GSM1670576 CELLOSAURUS
  GSM827472 CELLOSAURUS
  GSM887735 CELLOSAURUS
  GSM888830 CELLOSAURUS
IGRhCellID WM115 CELLOSAURUS
LiGeA CCLE_370 CELLOSAURUS
LINCS_HMS 50567 CELLOSAURUS
LINCS_LDP LCL-1260 CELLOSAURUS
Lonza 584 CELLOSAURUS
NCIt C3224 CELLOSAURUS
PharmacoDB WM115_1662_2019 CELLOSAURUS
Progenetix CVCL_0040 CELLOSAURUS
Wikidata Q54994157 CELLOSAURUS