CVCL_S661 - Rat Genome Database

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Cell Line : CVCL_S661 (MOLT-3/ZD1694.C) Homo sapiens

Symbol: CVCL_S661
Name: MOLT-3/ZD1694.C
RGD ID: 21113391
Cell Line Type: cancer cell line
Origin: Population: Caucasian; Selected for resistance to: ChEBI; CHEBI:5847; ICI D1694 (Tomudex; Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178; Cell type: T-cell; CL=CL_0000084.
Gender: Male
Genomic Alteration: Sequence variation: Mutation; HGNC; 7881; NOTCH1; Simple; p.Leu1600Pro (c.4799T>C); Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 7881; NOTCH1; Simple; p.Pro2514Argfs*4 (c.7541_7542delCT); ClinVar=VCV000581973; Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys267Argfs*9 (c.800delA) (p.Leu265fs, c.795delA); ClinVar=VCV000092828; Zygosity=Homozygous (from parent cell line)
Derived From Cell Lines: CVCL_0624 (MOLT-3)
Disease(s): T-cell adult acute lymphocytic leukemia (DOID:5602) [NCI:C9142]

References
Additional References at PubMed
PMID:8576277   PMID:8608962  


Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_S661 CELLOSAURUS
Cellosaurus CVCL_S661 CELLOSAURUS
NCIt C9142 CELLOSAURUS
Orphanet 99861 CELLOSAURUS
Wikidata Q54906363 CELLOSAURUS