Cell Line : CVCL_0029 (EFO-21) Homo sapiens
Symbol:	CVCL_0029
Name:	EFO-21
RGD ID:	21113386
Cell Line Type:	cancer cell line
Origin:	Population: Caucasian; Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Gender:	Female
Research Use:	Omics: CRISPR phenotypic screen; Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep quantitative proteome analysis; Omics: DNA methylation analysis; Omics: Genome sequenced; Omics: Protein expression by reverse-phase protein arrays; Omics: shRNA library screening; Omics: SNP array analysis; Omics: Transcriptome analysis by microarray; Omics: Transcriptome analysis by RNAseq
Phenotype:	Doubling time: 42 hours (PubMed=25984343); ~40-60 hours (DSMZ=ACC-235); 43.71 hours (GrayJW panel); Microsatellite instability: Stable (MSS) (PubMed=12661003; Sanger)
Genomic Alteration:	Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Cys124Arg (c.370T>C); Zygosity=Homozygous (Cosmic-CLP; DepMap)
Groups:	Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE); Part of: COSMIC cell lines project; Part of: MD Anderson Cell Lines Project
Description:	HLA typing: A*26:01,32:01; B*07:02,14:01; C*07:02,07:02 (PubMed=26589293); Genome ancestry: African=1.88%; Native American=0%; East Asian, North=4.99%; East Asian, South=0%; South Asian=0%; European, North=61.52%; European, South=31.61% (PubMed=30894373)
Child Cell Lines:	CVCL_RT14 (EFO-21rCDDP2000)
Aliases:	EFO 21; EFO21
Disease(s):	ovarian serous cystadenocarcinoma (DOID:5746) [NCI:C7978]

Additional References at PubMed

10 20 30 40 100 All Rows

PMID:6405069	PMID:12661003	PMID:20164919	PMID:22460905	PMID:23839242	PMID:25984343	PMID:26589293	PMID:27397505	PMID:28196595	PMID:30485824	PMID:30894373	PMID:30971826
PMID:31068700	PMID:35839778

10 20 30 40 100 All Rows

External Database Links

3 5 10 20 40 100 All Rows

Database	Acc Id	Source(s)
ArrayExpress	E-MTAB-2770	CELLOSAURUS
	E-MTAB-3610	CELLOSAURUS
	E-MTAB-783	CELLOSAURUS
BioGRID_ORCS_Cell_line	682	CELLOSAURUS
BioSample	SAMN03473384	CELLOSAURUS
	SAMN10988346	CELLOSAURUS
cancercelllines	CVCL_0029	CELLOSAURUS
Cell Line Ontology	CLO_0002892	CELLOSAURUS
Cell Model Passports	SIDM01052	CELLOSAURUS
Cellosaurus	CVCL_0029	CELLOSAURUS
ChEMBL-Cells	CHEMBL3308730	CELLOSAURUS
ChEMBL-Targets	CHEMBL1075440	CELLOSAURUS
COSMIC Samples	1305325	CELLOSAURUS
	1707571	CELLOSAURUS
	911905	CELLOSAURUS
Cosmic-CLP	911905	CELLOSAURUS
DepMap	ACH-000308	CELLOSAURUS
DSMZ	ACC-235	CELLOSAURUS
DSMZCellDive	ACC-235	CELLOSAURUS
EGA	EGAS00001000978	CELLOSAURUS
GDSC	911905	CELLOSAURUS
GEO	GSM1669756	CELLOSAURUS
	GSM274698	CELLOSAURUS
	GSM659374	CELLOSAURUS
	GSM711716	CELLOSAURUS
	GSM887000	CELLOSAURUS
	GSM888069	CELLOSAURUS
LiGeA	CCLE_252	CELLOSAURUS
LINCS_LDP	LCL-1515	CELLOSAURUS
NCIt	C7978	CELLOSAURUS
PharmacoDB	EFO21_325_2019	CELLOSAURUS
PRIDE	PXD030304	CELLOSAURUS
Progenetix	CVCL_0029	CELLOSAURUS
Wikidata	Q54832065	CELLOSAURUS

3 5 10 20 40 100 All Rows