CVCL_0028 - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Cell Line : CVCL_0028 (AN3-CA) Homo sapiens

Symbol: CVCL_0028
Name: AN3-CA
RGD ID: 21113384
Cell Line Type: cancer cell line
Origin: Derived from metastatic site: Lymph node.
Gender: Female
Research Use: Omics: Array-based CGH; Omics: ATAC-seq; Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: Protein expression by reverse-phase protein arrays; Omics: SNP array analysis; Omics: Transcriptome analysis
Phenotype: Doubling time: ~45-50 hours (CLS); ~55 hours (DSMZ); Microsatellite instability: Instable (MSI-high) (PubMed=31068700; Sanger)
Genomic Alteration: Sequence variation: Heterozygous for MAPK3 p.Pro373Ser (c.1117C>T) (ATCC); Sequence variation: Heterozygous for PIK3R1 p.Arg557_Lys561delArgGluIleAspLysinsGln (c.1670_1681delGAGAAATTGACA) (ATCC); Sequence variation: Homozygous for PTEN p.Arg130Glnfs*4 (c.389delG) (PubMed=20944090; ATCC); Sequence variation: Heterozygous for TP53 p.Gly389Trp (c.1165G>T) (ClinVar=VCV000156517) (ATCC)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: ERK genetic alteration cell panel (ATCC TCP-1033); Part of: MD Anderson Cell Lines Project; Part of: PTEN genetic alteration cell panel (ATCC TCP-1030)
Description: Genome ancestry: African=0.36%; Native American=0%; East Asian, North=0.85%; East Asian, South=1.08%; South Asian=3.21%; European, North=62.96%; European, South=31.54% (PubMed=30894373)
Aliases: Acanthosis Nigricans 3rd attempt-CArcinoma; AN-3; AN3; AN3 CA; AN3_CA; AN3CA
Disease(s): endometrial adenocarcinoma (DOID:2870) [NCI:C7359]

References
Additional References at PubMed
PMID:327080   PMID:3518877   PMID:6220172   PMID:14207855   PMID:20164919   PMID:20215515   PMID:20218740   PMID:20944090   PMID:22460905   PMID:22710073   PMID:25485619   PMID:27397505  
PMID:28196595   PMID:30894373   PMID:31068700  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-38 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
ATCC HTB-111 CELLOSAURUS
BCRJ 0363 CELLOSAURUS
BioSample SAMN03471092 CELLOSAURUS
  SAMN03473131 CELLOSAURUS
  SAMN03473336 CELLOSAURUS
  SAMN10988375 CELLOSAURUS
BTO BTO_0001771 CELLOSAURUS
CCRID 3142C0001000000098 CELLOSAURUS
Cell Line Ontology CLO_0001722 CELLOSAURUS
Cell Model Passports SIDM00901 CELLOSAURUS
Cellosaurus CVCL_0028 CELLOSAURUS
ChEMBL-Cells CHEMBL3308708 CELLOSAURUS
ChEMBL-Targets CHEMBL1075392 CELLOSAURUS
COSMIC Samples 1007162 CELLOSAURUS
  1057760 CELLOSAURUS
  1066221 CELLOSAURUS
  1070810 CELLOSAURUS
  1102376 CELLOSAURUS
  1105620 CELLOSAURUS
  1177683 CELLOSAURUS
  1223484 CELLOSAURUS
  1434192 CELLOSAURUS
  1576450 CELLOSAURUS
  1622894 CELLOSAURUS
  1696752 CELLOSAURUS
  2030460 CELLOSAURUS
  2646618 CELLOSAURUS
  687550 CELLOSAURUS
  699283 CELLOSAURUS
  713473 CELLOSAURUS
  713495 CELLOSAURUS
  809134 CELLOSAURUS
  846176 CELLOSAURUS
  871551 CELLOSAURUS
  889116 CELLOSAURUS
  910781 CELLOSAURUS
  980634 CELLOSAURUS
Cosmic-CLP 910781 CELLOSAURUS
DepMap ACH-000940 CELLOSAURUS
DSMZ ACC-267 CELLOSAURUS
EFO EFO_0002110 CELLOSAURUS
GDSC 910781 CELLOSAURUS
GEO GSM1669600 CELLOSAURUS
  GSM3161710 CELLOSAURUS
  GSM3161711 CELLOSAURUS
  GSM374970 CELLOSAURUS
  GSM375429 CELLOSAURUS
  GSM827494 CELLOSAURUS
  GSM886869 CELLOSAURUS
  GSM887934 CELLOSAURUS
IGRhCellID AN3CA CELLOSAURUS
LiGeA CCLE_574 CELLOSAURUS
LINCS_LDP LCL-1499 CELLOSAURUS
NCIt C7359 CELLOSAURUS
PharmacoDB AN3CA_63_2019 CELLOSAURUS
Progenetix CVCL_0028 CELLOSAURUS
Wikidata Q54749896 CELLOSAURUS