CVCL_0026 - Rat Genome Database

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Cell Line : CVCL_0026 (Capan-2) Homo sapiens

Symbol: CVCL_0026
Name: Capan-2
RGD ID: 21113382
Cell Line Type: cancer cell line
Gender: Male
Source: From: Memorial Sloan Kettering Cancer Center; New York; USA
Research Use: Omics: Array-based CGH; Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: Metabolome analysis; Omics: Proteome analysis by 2D-DE/MS; Omics: SNP array analysis; Omics: Transcriptome analysis
Phenotype: Doubling time: 96 hours (PubMed=3019537); 45-60 hours (CLS); ~50-70 hours (DSMZ); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Homozygous for CDKN2A p.Thr18_Ala19dup (c.52_57dupACGGCC) (ClinVar=VCV000579466) (PubMed=7972006; CCLE); Sequence variation: Heterozygous for KRAS p.Gly12Val (c.35G>T) (ClinVar=VCV000012583) (PubMed=7961102; PubMed=8026879; PubMed=8426738; PubMed=11169959; PubMed=15367885; CCLE; Cosmic-CLP); Sequence variation: Homozygous for TP53 p.Thr125Thr (c.375G>T) (ClinVar=VCV000237948); Note=Impairs TP53 splicing dramatically (PubMed=7961102; PubMed=8026879; PubMed=24700732; CCLE)
Caution: Caution: TP53 mutation indicated incorrectly as being at c.818G>A in PubMed=1630814
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: NCI RAS program mutant KRAS cell line panel; Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK2000-049
Description: Genome ancestry: African=0.28%; Native American=0.63%; East Asian, North=0.28%; East Asian, South=0%; South Asian=0.34%; European, North=62.52%; European, South=35.95% (PubMed=30894373)
Aliases: CANPAN-2; Capan 2; CaPan-2; Capan2
Disease(s): pancreatic ductal adenocarcinoma (DOID:3498) [NCI:C9120]

References
Additional References at PubMed
PMID:1630814   PMID:1764370   PMID:3019537   PMID:3518877   PMID:6582512   PMID:6935474   PMID:7459858   PMID:7809022   PMID:7961102   PMID:8026879   PMID:8286197   PMID:8426738  
PMID:10027410   PMID:11169957   PMID:11169959   PMID:12692724   PMID:12800145   PMID:14695172   PMID:15126341   PMID:15367885   PMID:15688027   PMID:15770730   PMID:18298655   PMID:18380791  
PMID:20164919   PMID:20215515   PMID:20418756   PMID:22460905   PMID:22585861   PMID:24700732   PMID:25167228   PMID:25485619   PMID:26216984   PMID:27259358   PMID:27397505   PMID:30894373  
PMID:31037374   PMID:31068700  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-38 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
ATCC HTB-80 CELLOSAURUS
BCRJ 0060 CELLOSAURUS
BioSample SAMN03472025 CELLOSAURUS
  SAMN03473387 CELLOSAURUS
  SAMN10988212 CELLOSAURUS
BTO BTO_0002745 CELLOSAURUS
Cell Line Ontology CLO_0002198 CELLOSAURUS
Cell Model Passports SIDM00943 CELLOSAURUS
CelloPub CLPUB00416 CELLOSAURUS
Cellosaurus CVCL_0026 CELLOSAURUS
ChEMBL-Cells CHEMBL3308720 CELLOSAURUS
ChEMBL-Targets CHEMBL1075417 CELLOSAURUS
COSMIC Samples 1006366 CELLOSAURUS
  1108339 CELLOSAURUS
  1299297 CELLOSAURUS
  1320463 CELLOSAURUS
  1366277 CELLOSAURUS
  1571775 CELLOSAURUS
  1995363 CELLOSAURUS
  2009527 CELLOSAURUS
  2046535 CELLOSAURUS
  2434087 CELLOSAURUS
  2668288 CELLOSAURUS
  730527 CELLOSAURUS
  736271 CELLOSAURUS
  755303 CELLOSAURUS
  808163 CELLOSAURUS
  868246 CELLOSAURUS
  910915 CELLOSAURUS
  913303 CELLOSAURUS
  922256 CELLOSAURUS
  923167 CELLOSAURUS
  932517 CELLOSAURUS
  932987 CELLOSAURUS
  933522 CELLOSAURUS
  934554 CELLOSAURUS
  947396 CELLOSAURUS
  948727 CELLOSAURUS
  949232 CELLOSAURUS
Cosmic-CLP 910915 CELLOSAURUS
DepMap ACH-000107 CELLOSAURUS
DOI 10.4172/jpb.1000057 CELLOSAURUS
DSMZ ACC-245 CELLOSAURUS
EFO EFO_0002154 CELLOSAURUS
GDSC 910915 CELLOSAURUS
GEO GSM1024399 CELLOSAURUS
  GSM1374440 CELLOSAURUS
  GSM1669664 CELLOSAURUS
  GSM206453 CELLOSAURUS
  GSM621896 CELLOSAURUS
  GSM784710 CELLOSAURUS
  GSM886921 CELLOSAURUS
  GSM887987 CELLOSAURUS
IGRhCellID Capan2 CELLOSAURUS
KCLB 30080 CELLOSAURUS
LiGeA CCLE_178 CELLOSAURUS
LINCS_LDP LCL-1733 CELLOSAURUS
Lonza 1464 CELLOSAURUS
MetaboLights MTBLS812 CELLOSAURUS
NCIt C9120 CELLOSAURUS
PharmacoDB Capan2_185_2019 CELLOSAURUS
PRIDE PXD003198 CELLOSAURUS
Progenetix CVCL_0026 CELLOSAURUS
Wikidata Q54808591 CELLOSAURUS