CVCL_0060 - Rat Genome Database

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Cell Line : CVCL_0060 (NCI-H1299) Homo sapiens

Symbol: CVCL_0060
Name: NCI-H1299
RGD ID: 21113347
Cell Line Type: cancer cell line
Origin: Derived from metastatic site: Lymph node.
Gender: Male
Research Use: Omics: Deep exome analysis; Omics: Deep quantitative proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: Protein expression by reverse-phase protein arrays; Omics: shRNA library screening; Omics: SNP array analysis; Omics: Transcriptome analysis
Phenotype: Doubling time: 30 hours (PubMed=25984343); 22.5 hours (PubMed=29681454); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Heterozygous for NRAS p.Gln61Lys (c.181C>A) (ClinVar=VCV000073058) (PubMed=1311061; PubMed=12068308; ATCC; CCLE; Cosmic-CLP); Sequence variation: Gene deletion; TP53; Zygosity=Homozygous (PubMed=1311061; PubMed=1565469; ATCC)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: KuDOS 95 cell line panel; Part of: MD Anderson Cell Lines Project
Description: HLA typing: A*24:02,32:01:01; B*40:01,40:02:01; C*03:03:01,02:02:02 (PubMed=26929325); Genome ancestry: African=0.33%; Native American=0%; East Asian, North=2.13%; East Asian, South=0%; South Asian=0%; European, North=62.86%; European, South=34.68% (PubMed=30894373)
Child Cell Lines: CVCL_XB24 (NCI-H1299-mCherry)
CVCL_XB25 (NCI-H1299-EGFP)
CVCL_XB26 (NCI-H1299-tdT)
CVCL_XE62 (NCI-H1299-Luc2-tdT-2)
CVCL_Y296 (H273)
Aliases: H-1299; H1299; HI299; NCIH1299
Disease(s): lung large cell carcinoma (DOID:4556) [NCI:C4450]

References
Additional References at PubMed
PMID:1311061   PMID:1563005   PMID:1565469   PMID:8806092   PMID:11030152   PMID:12068308   PMID:17332333   PMID:18083107   PMID:19472407   PMID:20215515   PMID:20679594   PMID:22460905  
PMID:22961666   PMID:24335698   PMID:25485619   PMID:25984343   PMID:26929325   PMID:27397505   PMID:28196595   PMID:29444439   PMID:29681454   PMID:30038707   PMID:30894373   PMID:31068700  
PMID:31803961   PMID:31978347  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-2706 CELLOSAURUS
  E-MTAB-2770 CELLOSAURUS
  E-MTAB-3610 CELLOSAURUS
  E-MTAB-783 CELLOSAURUS
ATCC CRL-5803 CELLOSAURUS
BCRJ 0185 CELLOSAURUS
BioSample SAMN03471642 CELLOSAURUS
  SAMN03471739 CELLOSAURUS
  SAMN10988385 CELLOSAURUS
BTO BTO_0002552 CELLOSAURUS
CCRID 3111C0001CCC000469 CELLOSAURUS
  3111C0002000000050 CELLOSAURUS
  3131C0001000700160 CELLOSAURUS
  3142C0001000000947 CELLOSAURUS
Cell Line Ontology CLO_0007986 CELLOSAURUS
Cell Model Passports SIDM00649 CELLOSAURUS
Cellosaurus CVCL_0060 CELLOSAURUS
ChEMBL-Cells CHEMBL3308501 CELLOSAURUS
ChEMBL-Targets CHEMBL612255 CELLOSAURUS
COSMIC Samples 1004693 CELLOSAURUS
  1032443 CELLOSAURUS
  1047106 CELLOSAURUS
  1066159 CELLOSAURUS
  1146875 CELLOSAURUS
  1154606 CELLOSAURUS
  1175867 CELLOSAURUS
  1218870 CELLOSAURUS
  1239925 CELLOSAURUS
  1609524 CELLOSAURUS
  1870264 CELLOSAURUS
  1925845 CELLOSAURUS
  1995520 CELLOSAURUS
  2042873 CELLOSAURUS
  2125178 CELLOSAURUS
  2630419 CELLOSAURUS
  2664126 CELLOSAURUS
  2749161 CELLOSAURUS
  2772159 CELLOSAURUS
  722069 CELLOSAURUS
  724831 CELLOSAURUS
  877265 CELLOSAURUS
  877418 CELLOSAURUS
  903585 CELLOSAURUS
  961838 CELLOSAURUS
  980971 CELLOSAURUS
Cosmic-CLP 724831 CELLOSAURUS
DepMap ACH-000510 CELLOSAURUS
EFO EFO_0003043 CELLOSAURUS
GDSC 724831 CELLOSAURUS
GEO GSM1374698 CELLOSAURUS
  GSM1374699 CELLOSAURUS
  GSM1670165 CELLOSAURUS
  GSM185871 CELLOSAURUS
  GSM206471 CELLOSAURUS
  GSM253382 CELLOSAURUS
  GSM274743 CELLOSAURUS
  GSM274744 CELLOSAURUS
  GSM353229 CELLOSAURUS
  GSM434266 CELLOSAURUS
  GSM784253 CELLOSAURUS
  GSM794311 CELLOSAURUS
  GSM827467 CELLOSAURUS
  GSM844617 CELLOSAURUS
  GSM887355 CELLOSAURUS
  GSM888433 CELLOSAURUS
IGRhCellID H1299GEO CELLOSAURUS
KCLB 25803 CELLOSAURUS
  91299 CELLOSAURUS
LiGeA CCLE_300 CELLOSAURUS
LINCS_LDP LCL-1609 CELLOSAURUS
Lonza 796 CELLOSAURUS
NCIt C4450 CELLOSAURUS
PharmacoDB NCIH1299_1006_2019 CELLOSAURUS
PRIDE PXD003743 CELLOSAURUS
  PXD018581 CELLOSAURUS
Progenetix CVCL_0060 CELLOSAURUS
Wikidata Q5628772 CELLOSAURUS