CVCL_IN16 - Rat Genome Database

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Cell Line : CVCL_IN16 (MDA-MB-231 CMV) Homo sapiens

Symbol: CVCL_IN16
Name: MDA-MB-231 CMV
RGD ID: 21111810
Cell Line Type: cancer cell line
Origin: Derived from metastatic site: Pleural effusion.
Gender: Female
Research Use: Omics: Transcriptome analysis
Characteristics: Characteristics: Control cell line for the MDA-MB-231 ERalpha (CVCL_IN17), MDA-MB-231 ERalpha203/4/11 (CVCL_IN15), MDA-MB-231 ERbeta (CVCL_IN18) and MDA-MB-231 ERbetaDBD (CVCL_IN19) cell lines
Genomic Alteration: Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line); Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Homozygous (from parent cell line)
Groups: Group: Triple negative breast cancer (TNBC) cell line
Derived From Cell Lines: CVCL_0062 (MDA-MB-231)
Aliases: MDA Mb231 (CMV)
Disease(s): breast adenocarcinoma (DOID:3458) [NCI:C5214]

References
Additional References at PubMed
PMID:19321454  


Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_IN16 CELLOSAURUS
GEO GSM246267 CELLOSAURUS
  GSM246268 CELLOSAURUS
  GSM246269 CELLOSAURUS
  GSM246270 CELLOSAURUS
  GSM246271 CELLOSAURUS
  GSM246272 CELLOSAURUS
  GSM246285 CELLOSAURUS
  GSM246286 CELLOSAURUS
  GSM246287 CELLOSAURUS
  GSM246288 CELLOSAURUS
  GSM246289 CELLOSAURUS
  GSM246290 CELLOSAURUS
NCIt C5214 CELLOSAURUS
Wikidata Q54904582 CELLOSAURUS