CVCL_8442 - Rat Genome Database

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Cell Line : CVCL_8442 (MOBS-1) Homo sapiens

Symbol: CVCL_8442
Name: MOBS-1
RGD ID: 21108994
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Pleural effusion.
Gender: Male
Phenotype: Doubling time: 12 hours (DOI=10.15369/sujms1989.9.45)
Genomic Alteration: Sequence variation: Gene fusion; PICALM-MLLT10 (CALM-AF10) (from parent cell line); Sequence variation: Hemizygous for PTEN p.Gly129fs*51 (c.387_388insCGCC) (from parent cell line); Sequence variation: Homozygous for TP53 c.559+1G>A (p.Val173Trpfs*59) (ClinVar=VCV000428908); Note=Splice donor mutation (from parent cell line)
Caution: Problematic cell line: Contaminated Shown to be a U-937 derivative (PubMed=12592342; PubMed=20143388). Originally thought to originate from the peripheral blood of a 57 year old male patient with monocytic leukemia (M5b).
Groups: Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00239
Derived From Cell Lines: CVCL_0007 (U-937)
Child Cell Lines: CVCL_RX32 (MABS-1)
Disease(s): adult acute monocytic leukemia (DOID:0080149) [NCI:C8263]

Additional References at PubMed
PMID:12592342   PMID:20143388  

Additional Information

Database Acc Id Source(s)
BioSample SAMN03151984 CELLOSAURUS
Cellosaurus CVCL_8442 CELLOSAURUS
DOI 10.15369/sujms1989.9.45 CELLOSAURUS
Orphanet 514 CELLOSAURUS
Wikidata Q54906291 CELLOSAURUS