Cell Line : CVCL_II77 (HL-60/S4) Homo sapiens
|Cell Line Type:
||cancer cell line
||Transformant: N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)(ChEBI; CHEBI:21759); Derived from sampling site: Peripheral blood.
||Omics: DNA methylation analysis
||Characteristics: Differentiation to a granulocyte-like state can be induced by retinoic acid (RA)
||Sequence variation: Homozygous for CDKN2A p.Arg80Ter (c.238C>T) (p.Pro94Leu; c.281C>T) (ClinVar=VCV000009409) (from parent cell line); Sequence variation: Heterozygous for NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (from parent cell line); Sequence variation: Gene deletion; TP53; Zygosity=Homozygous (from parent cell line)
|Derived From Cell Lines: