CVCL_GZ72 - Rat Genome Database

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Cell Line : CVCL_GZ72 (U266/ADM) Homo sapiens

Symbol: CVCL_GZ72
Name: U266/ADM
RGD ID: 21093828
Cell Line Type: cancer cell line
Origin: Population: Caucasian; Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Gender: Male
Characteristics: Characteristics: Produces IgE lambda (from parent cell line)
Genomic Alteration: Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Lys601Asn (c.1803A>T); ClinVar=VCV000376285; Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 7329; MSH6; Simple; p.Gly141Asp (c.422G>A); ClinVar=VCV001491786; Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line); Sequence variation: Mutation; HGNC; 12033; TRAF3; Simple; p.Lys550Leufs*3 (c.1648_1649insT); Zygosity=Homozygous (from parent cell line)
Derived From Cell Lines: CVCL_0566 (U266B1)
Disease(s): multiple myeloma (DOID:9538) [NCI:C3242,ORDO:29073]

References
Additional References at PubMed
PMID:26045737  


Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_GZ72 CELLOSAURUS
Cellosaurus CVCL_GZ72 CELLOSAURUS
NCIt C3242 CELLOSAURUS
Orphanet 29073 CELLOSAURUS
Wikidata Q54973632 CELLOSAURUS