CVCL_XZ66 - Rat Genome Database

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Cell Line : CVCL_XZ66 (U87MG Human EGFR vIII) Homo sapiens

Symbol: CVCL_XZ66
Name: U87MG Human EGFR vIII
RGD ID: 21085206
Cell Line Type: cancer cell line
Gender: Male
Phenotype: Doubling time: ~30 hours (KYinno)
Genomic Alteration: Sequence variation: Heterozygous for NF1 p.Phe1247Ilefs*18 (c.3739_3742delTTTG) (3737_3740delTGTT) (ClinVar=VCV000420078) (from parent cell line); Sequence variation: Homozygous for PTEN c.209+1G>T (ClinVar=VCV000229705); Note=Splice donor mutation (from parent cell line); Sequence variation: TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (from parent cell line); Transfected with: HGNC; 3236; EGFR (with p.Val30_Arg297del = EGFRvIII); Transfected with: UniProtKB; P13249; S.alboniger pac.
Related Genes: EGFR  
Derived From Cell Lines: CVCL_0022 (U-87MG ATCC)
Disease(s): glioblastoma (DOID:3068) [NCI:C3058]

References

Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_XZ66 CELLOSAURUS
NCIt C3058 CELLOSAURUS
Orphanet 360 CELLOSAURUS
Wikidata Q98133791 CELLOSAURUS