CVCL_XZ65 - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Cell Line : CVCL_XZ65 (THP-1 NF-kb luciferase reporter) Homo sapiens

Symbol: CVCL_XZ65
Name: THP-1 NF-kb luciferase reporter
RGD ID: 21085205
Cell Line Type: cancer cell line
Origin: Population: Japanese; Derived from sampling site: Peripheral blood.
Gender: Male
Characteristics: Characteristics: The luciferase reporter gene is under the control of the NF-kappaB response element
Phenotype: Doubling time: ~48 hours (KYinno)
Genomic Alteration: Sequence variation: Gene fusion; CSNK2A1-DDX39B (from parent cell line); Sequence variation: Gene fusion; KMT2A-MLLT3 (MLL-MLLT3; MLL-AF9) (from parent cell line); Sequence variation: Heterozygous for NRAS p.Gly12Asp (c.35G>A) (ClinVar=VCV000039648) (from parent cell line); Sequence variation: Heterozygous for TP53 p.Arg174fs*3 (c.520_545del26) (from parent cell line); Transfected with: UniProtKB; P08659; Firefly luciferase; Transfected with: UniProtKB; P00557; E.coli hygromycin-B 4-O-kinase (hph)
Derived From Cell Lines: CVCL_0006 (THP-1)


Additional Information

Database Acc Id Source(s)
Orphanet 514 CELLOSAURUS
Wikidata Q98133244 CELLOSAURUS