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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1565122
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ttc21b
Name: tetratricopeptide repeat domain 21B
Acc ID: CHEBI:9986
Term: vinclozolin
Definition: A racemate comprising equimolar amounts of (R)- and (S)-vinclozolin. A fungicide used mainly on oilseed rape, vines, fruit and vegetables to control Botrytis, Sclerotinia and Monilia spp.
Chemical ID: MESH:C025643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ttc21bdecreases expressionEXP 6480464CTDvinclozolin results in decreased expression of TTC21B mRNAPMID:23034163
Ttc21bdecreases methylationEXP 6480464CTDvinclozolin results in decreased methylation of TTC21B genePMID:30207508
Ttc21bincreases methylationEXP 6480464CTDvinclozolin results in increased methylation of TTC21B genePMID:31682807
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