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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319584
Species: Homo sapiens
RGD Object: Gene
Symbol: MDM4
Name: MDM4 regulator of p53
Acc ID: CHEBI:9986
Term: vinclozolin
Definition: A racemate comprising equimolar amounts of (R)- and (S)-vinclozolin. A fungicide used mainly on oilseed rape, vines, fruit and vegetables to control Botrytis, Sclerotinia and Monilia spp.
Chemical ID: MESH:C025643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MDM4decreases expressionISOMdm4 (Rattus norvegicus)6480464CTDvinclozolin results in decreased expression of MDM4 mRNAPMID:22570695 PMID:23034163
MDM4increases expressionISOMdm4 (Rattus norvegicus)6480464CTDvinclozolin results in increased expression of MDM4 mRNAPMID:20566332 PMID:23034163 PMID:23555832
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