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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2346
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chrna4
Name: cholinergic receptor nicotinic alpha 4 subunit
Acc ID: CHEBI:9940
Term: vecuronium bromide
Definition: The organic bromide salt of a 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidinino- and 16beta-N-methylpiperidinium substituents.
Chemical ID: MESH:D014673
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrna4multiple interactionsISORGD:103566480464CTDVecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]PMID:14645658 PMID:16931985
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