GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GADD45A | affects response to substance | EXP | | 6480464 | CTD | GADD45A protein affects the susceptibility to troglitazone | PMID:15064713 | GADD45A | increases expression | EXP | | 6480464 | CTD | troglitazone results in increased expression of GADD45A mRNA; troglitazone results in increased expression of GADD45A protein | PMID:15064713 PMID:19022234 PMID:19631733 | GADD45A | multiple interactions | EXP | | 6480464 | CTD | troglitazone inhibits the reaction [pyrazolanthrone results in increased expression of GADD45A mRNA]; troglitazone inhibits the reaction [pyrazolanthrone results in increased expression of GADD45A protein]; troglitazone promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased expression of GADD45A mRNA]; troglitazone promotes the reaction [SB 203580 results in increased expression of GADD45A mRNA] | PMID:15064713 | GADD45A | increases expression | ISO | Gadd45a (Rattus norvegicus) | 6480464 | CTD | troglitazone results in increased expression of GADD45A mRNA; troglitazone results in increased expression of GADD45A protein | PMID:11068018 | | ||||||||||||||||||||||
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