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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732278
Species: Homo sapiens
RGD Object: Gene
Symbol: ECH1
Name: enoyl-CoA hydratase 1
Acc ID: CHEBI:9753
Term: troglitazone
Definition: A chromane that has formula C24H27NO5S.
Chemical ID: MESH:C057693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ECH1multiple interactionsEXP 6480464CTD[Oleic Acid co-treated with troglitazone] results in increased expression of ECH1 mRNAPMID:24534255
ECH1increases expressionISOEch1 (Rattus norvegicus)6480464CTDtroglitazone results in increased expression of ECH1 mRNA; troglitazone results in increased expression of ECH1 proteinPMID:21315101 PMID:21515302
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