GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccn2 | decreases expression | ISO | CCN2 (Homo sapiens) | 6480464 | CTD | Troglitazone results in decreased expression of CCN2 mRNA | PMID:25572481 | Ccn2 | increases expression | ISO | CCN2 (Homo sapiens) | 6480464 | CTD | Troglitazone results in increased expression of CCN2 mRNA | PMID:19140230 | Ccn2 | multiple interactions | ISO | CCN2 (Homo sapiens) | 6480464 | CTD | [Troglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA; Troglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CCN2 mRNA]; Troglitazone inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA]; Troglitazone inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] | PMID:17056281 PMID:19429239 PMID:20847119 | |
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