GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fasn | decreases expression | EXP | | 6480464 | CTD | troglitazone results in decreased expression of FASN mRNA | PMID:19022234 | Fasn | multiple interactions | EXP | | 6480464 | CTD | [[[troglitazone binds to and results in increased activity of PPARG protein] which results in decreased localization of and results in decreased activity of SREBF1 protein] which results in decreased expression of FASN mRNA] which results in decreased abundance of Triglycerides | PMID:19248225 | Fasn | increases expression | ISO | FASN (Homo sapiens) | 6480464 | CTD | troglitazone results in increased expression of FASN mRNA | PMID:19022234 | | ||||||||||||||||||||||
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