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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 14043101
Species: Sus scrofa
RGD Object: Gene
Symbol: INS
Name: insulin
Acc ID: CHEBI:9753
Term: troglitazone
Definition: A chromane that has formula C24H27NO5S.
Chemical ID: MESH:C057693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
INSmultiple interactionsEXP 6480464CTDTroglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 protein modified form]PMID:11889176
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