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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10681
Species: Mus musculus
RGD Object: Gene
Symbol: Gpx1
Name: glutathione peroxidase 1
Acc ID: CHEBI:9753
Term: troglitazone
Definition: A chromane that has formula C24H27NO5S.
Chemical ID: MESH:C057693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpx1decreases expressionISOGpx1 (Rattus norvegicus)6480464CTDtroglitazone results in decreased expression of GPX1 proteinPMID:11328671
Gpx1increases expressionISOGpx1 (Rattus norvegicus)6480464CTDtroglitazone results in increased expression of GPX1 proteinPMID:21315101
Gpx1increases expressionISOGPX1 (Homo sapiens)6480464CTDtroglitazone results in increased expression of GPX1 mRNAPMID:19631733
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