GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cebpa | increases expression | EXP | | 6480464 | CTD | troglitazone results in increased expression of CEBPA mRNA | PMID:12732648 PMID:19682441 PMID:24559133 PMID:8895337 | Cebpa | multiple interactions | EXP | | 6480464 | CTD | (+)-JQ1 compound inhibits the reaction [[INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Troglitazone] results in increased expression of CEBPA protein]; [INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Troglitazone] results in increased expression of CEBPA protein; JMJD6 mutant form inhibits the reaction [[INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Troglitazone] results in increased expression of CEBPA protein] | PMID:26117538 | Cebpa | decreases expression | ISO | Cebpa (Rattus norvegicus) | 6480464 | CTD | troglitazone results in decreased expression of CEBPA mRNA | PMID:19022234 | Cebpa | increases expression | ISO | CEBPA (Homo sapiens) | 6480464 | CTD | troglitazone results in increased expression of CEBPA mRNA | PMID:19022234 | Cebpa | multiple interactions | ISO | CEBPA (Homo sapiens) | 6480464 | CTD | [1-Methyl-3-isobutylxanthine co-treated with troglitazone co-treated with INS protein] results in increased expression of CEBPA mRNA; troglitazone inhibits the reaction [TNF protein inhibits the reaction [INS protein results in increased expression of CEBPA mRNA]] | PMID:27003841 PMID:7956951 | | ||||||||||||||||||||||
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