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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732441
Species: Homo sapiens
RGD Object: Gene
Symbol: TXN
Name: thioredoxin
Acc ID: CHEBI:9747
Term: Triptolide
Definition: An oxacycle that has formula C20H24O6.
Chemical ID: MESH:C001899
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TXNdecreases expressionEXP 6480464CTDtriptolide results in decreased expression of TXN proteinPMID:30394310
TXNmultiple interactionsEXP 6480464CTDNOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of TXN protein]PMID:30394310
TXNdecreases expressionISOTxn1 (Mus musculus)6480464CTDtriptolide results in decreased expression of TXN proteinPMID:30394310
TXNmultiple interactionsISOTxn1 (Mus musculus)6480464CTDNOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of TXN protein]PMID:30394310
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