Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	10132
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Akt2
Name:	thymoma viral proto-oncogene 2

Acc ID:	CHEBI:9747
Term:	Triptolide
Definition:	An oxacycle that has formula C20H24O6.
Chemical ID:	MESH:C001899

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Akt2	decreases expression	ISO	Akt2 (Rattus norvegicus)	6480464	CTD	triptolide results in decreased expression of AKT2 mRNA	PMID:23639586

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.