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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp11b3
Name: cytochrome P450, family 11, subfamily b, polypeptide 3
Acc ID: CHEBI:9637
Term: torasemide
Definition: An N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure.
Chemical ID: MESH:C026116
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11b3affects expressionEXP 6480464CTDTorsemide affects the expression of CYP11B2 proteinPMID:18001696
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