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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551988
Species: Mus musculus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase family, member 1
Acc ID: CHEBI:9631
Term: Tomentosin
Definition: A sesquiterpene lactone that has formula C15H20O3.
Chemical ID: MESH:C454646
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1increases cleavageISOPARP1 (Homo sapiens)6480464CTDtomentosin results in increased cleavage of PARP1 proteinPMID:27922187 PMID:30917517
Parp1multiple interactionsISOPARP1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [tomentosin results in increased cleavage of PARP1 protein]PMID:30917517
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