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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730821
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP2
Name: matrix metallopeptidase 2
Acc ID: CHEBI:9629
Term: tomatidine
Definition: A 3beta-hydroxy steroid resulting from the substitution of the 3beta-hydrogen of tomatidane by a hydroxy group.
Chemical ID: MESH:C003677
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP2decreases expressionEXP 6480464CTDtomatidine results in decreased expression of MMP2 mRNA; tomatidine results in decreased expression of MMP2 proteinPMID:23566884 PMID:31545954
MMP2multiple interactionsEXP 6480464CTDtomatidine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein modified form]PMID:31545954
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