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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10765
Species: Mus musculus
RGD Object: Gene
Symbol: Igf1
Name: insulin-like growth factor 1
Acc ID: CHEBI:9607
Term: Tiron
Definition: An organic molecular entity that has formula C6H4O8S2.2Na.
Chemical ID: MESH:D014013
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igf1multiple interactionsISOIGF1 (Homo sapiens)6480464CTD1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of IRS1 protein]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein]PMID:17458902
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